Sort   by:  
 Page size 
GenomicsIndividual-specific and allele-specific chromatin signatures in diverse human populations
This dataset contains DNase-seq data and CTCF ChIP-seq data for 6 lymphoblastoid cell lines. There are 3 cell lines from a YRI trio and 3 lines from a CEU trio (HapMap GM19238, GM19239, GM 19240, GM12891, GM12892, GM12878). For data usage terms and conditions, please refer to http://www.genome.gov/...
ORGANISM(S): Homo sapiens 
2010-03-15 | E-GEOD-19622 | biostudies-arrayexpress
TranscriptomicsInduction of Senescence in Diterpene Ester-Treated Melanoma Cells via PKC-dependent Hyperactivation of the MAPK Pathway
The diterpene ester PEP005 is a novel anticancer agent that activates PKC and cures subcutaneous murine melanoma by topical application. We now describe the in vitro cytostatic effects of PEP005 and the diterpene ester TPA, observed in 20% of human melanoma cell lines. Primary cultures of normal h...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-3484 | biostudies-arrayexpress
GenomicsLRH-1 governs vital transcriptional programs in endocrine sensitive and resistant breast cancer cells: LRH-1 ChIP-seq
Tumor characteristics are decisive in the determination of treatment strategy for breast cancer patients. Patients with estrogen receptor a(ERa)-positive breast cancer can benefit from long-term hormonal treatment. Nonetheless, the majority of patients will develop resistance to these therapies. Her...
ORGANISM(S): Homo sapiens 
2014-02-27 | E-GEOD-47027 | biostudies-arrayexpress
Genomicsena-DATASET-ICR-GM-05-05-2015-22:13:47:053-131 - samples
463 newly diagnosed patients from the UK Myeloma XI clinical trial (NCT01554852) underwent whole exome sequencing plus targeted capture of the IGH/K/L and MYC loci. 200 ng of DNA were processed using NEBNext DNA library prepartion kit and hybridised to the SureSelect Human All Exon V5 Plus. Four s...
EGAD00001001358 | EGA
TranscriptomicsHF liver: Control vs. Plin2-ASO treated
Transcriptional profiling of mouse liver comparing control, scrambled-oligonucleotides (Cont)-treated mice with Perilipin 2-antisense oligonucleotides (Plin2-ASO)-treated mice. C57BL/6 mice on a high-fat diet were treated with oligonucleotides in vivo. The goal was to determine the effects of Plin2 ...
ORGANISM(S): Mus musculus 
2012-12-05 | E-GEOD-37011 | biostudies-arrayexpress
ProteomicsProteogenomic Landscape of Squamous Cell Lung Cancer 2: Tandem Mass Tag Datasets
We report an integrated analysis incorporating DNA copy number analyses, somatic exon mutations, mRNA expression via RNA-sequencing, and shotgun mass spectrometry analysis of protein abundance in 108 surgically resected squamous cell lung cancers (SCC) with accompanying clinical outcome, evaluation ...
ORGANISM(S): Homo sapiens (Human) 
2019-05-24 | PXD010429 | Pride
Human Tmt Squamous cell carcinoma Lung cancer 
ProteomicsProteogenomic Landscape of Squamous Cell Lung Cancer 1: Digestion QC with DIA LC-MS/MS
We report an integrated analysis incorporating DNA copy number analyses, somatic exon mutations, mRNA expression via RNA-sequencing, and shotgun mass spectrometry analysis of protein abundance in 108 surgically resected squamous cell lung cancers (SCC) with accompanying clinical outcome, evaluation ...
ORGANISM(S): Homo sapiens (Human) 
2019-05-24 | PXD010357 | Pride
Human Dia Squamous cell carcinoma Lung cancer 
UnknownThe National Lung Screening Trial: overview and study design.
Not available
S-EPMC3009383 | biostudies-literature
UnknownEffect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial.
Not available
S-EPMC3835156 | biostudies-literature
UnknownResistance of Dynamin-related Protein 1 Oligomers to Disassembly Impairs Mitophagy, Resulting in Myocardial Inflammation and Heart Failure.
Not available
S-EPMC4646246 | biostudies-literature
Sort   by:  
 Page size