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MetabolomicsLipodomics and Gestational bisphenol A (BPA) exposure
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ORGANISM(S): Ovis aries 
ST000686 | MetabolomicsWorkbench
TranscriptomicsHigh intake of dietary sugar enhances bisphenol A (BPA) disruption and reveals ribosome-mediated pathways of toxicity: Chronic Exposure
Fly strain y[1]; bw[1]; e[4]; ci[1] ey[R] was obtained from the Bloomington Stock Center. Flies were reared in incubators at 25°C, 65% of relative humidity, and photoperiod of 12 hours. For gene expression analyses flies were reared in media containing BPA, high sugar, and BPA + high sugar (chronic ...
ORGANISM(S): Drosophila melanogaster 
2014-06-04 | E-GEOD-55670 | biostudies-arrayexpress
TranscriptomicsBisphenol A Exposure and Multiple Sclerosis Risk
Bisphenol A Exposure and Multiple Sclerosis Risk Comparison of vehicle-treated vs. BPA-treated mouse testes tissue. Each comparison in technical and biological duplicate (Done twice: total 4 replicates)
ORGANISM(S): Mus musculus 
2013-10-22 | E-GEOD-45917 | biostudies-arrayexpress
TranscriptomicsBPA impacts on HEK 293 cells
Bisphenol A (BPA) is an environmental endocrine disruptor which has been detected in almost all human bodies. Many studies have implied that BPA exposure is harmful to human health. Previous studies mainly focused on BPA effects on ER-positive cells. Genome-wide impact of BPA on gene regulation in E...
ORGANISM(S): Homo sapiens 
2014-10-10 | E-MTAB-1959 | biostudies-arrayexpress
TranscriptomicsGene expression changes in the fetal rhesus monkey uterus from early to late gestation and the effects of in utero exposure to BPA
We used the rhesus monkey (Macaca mulatta) as our animal model for the current study with two goals: to characterize the changes in histology and gene expression from early to late gestation (prenatal uterine organogenesis) and to determine if there are effects of prenatal exposure to bisphenol A (B...
ORGANISM(S): Macaca mulatta 
2014-05-22 | E-GEOD-38421 | biostudies-arrayexpress
TranscriptomicsEffects of bisphenol A on gene expression in adipocytes from lean children: association to metabolic disorders
Bisphenol A (BPA) is a xenobiotic endocrine disrupting chemical. In vitro and in vivo studies indicated that BPA alters endocrine-metabolic pathways in adipose tissue increasing the risk of developing metabolic disorders. BPA effects on human adipocytes, specifically in children, are poorly investig...
ORGANISM(S): Homo sapiens 
2015-07-09 | E-GEOD-58516 | biostudies-arrayexpress
TranscriptomicsHigh intake of dietary sugar enhances bisphenol A (BPA) disruption and reveals ribosome-mediated pathways of toxicity: Acute Exposure
Fly strain y[1]; bw[1]; e[4]; ci[1] ey[R] was obtained from the Bloomington Stock Center. Flies were reared in incubators at 25°C, 65% of relative humidity, and photoperiod of 12 hours. For gene expression analyses flies were exposed to BPA, DEHP, and high sugar for 48 hours (acute exposure). After ...
ORGANISM(S): Drosophila melanogaster 
2014-06-04 | E-GEOD-55655 | biostudies-arrayexpress
TranscriptomicsEffects of low and high doses of bisphenol A on mouse liver transcriptome
Bisphenol A (BPA) is used in the plastic industry as the monomer of polycarbonates and epoxy resins. Heat and changes in pH conditions lead to its leakage from the plastics in which it is incorporated. This largely contributes to the widespread exposure of the general population to this environmenta...
ORGANISM(S): Mus musculus 
2011-09-20 | E-GEOD-26728 | biostudies-arrayexpress
TranscriptomicsGene Expression Analysis of Human Endometrial Endothelial Cells Exposed to Bisphenol A
The endocrine disrupting chemical bisphenol A (BPA) can affect reproductive organs, tissues and cells in several species. Treatment of human endometrial endothelial cells (HEECs) with 50 µM BPA decreased their proliferation compared with the control. Microarray analyses revealed that BPA affected b...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-10802 | biostudies-arrayexpress
TranscriptomicsAssessment of low-dose BPA toxicity in thyroid follicular cells by gene expression microarray.
Gene expression microarrays were performed to investigate the molecular effects of exposure to BPA on thyrocytes (FRTL-5). Cells were treated with low-lose BPA (10^-9 M) at different time points to analyse time dependent toxicity.
ORGANISM(S): Rattus norvegicus 
2016-02-29 | E-MTAB-4458 | biostudies-arrayexpress
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