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TranscriptomicsA Genetic Interaction Map of RNA Processing Factors Reveals Links Between mRNA Processing Complexes
All classes of RNA undergo processing. The two largest RNA processing complexes are those involved in rRNA biogenesis and mRNA splicing. Because of their complexity and essential roles, it has been difficult to dissect the functional interactions within these machines as well as to identify possible...
ORGANISM(S): Saccharomyces cerevisiae 
2008-12-30 | E-GEOD-11634 | biostudies-arrayexpress
TranscriptomicsKaplan2013: High-Resolution, Quantitative Genetic Analysis of RNA Polymerase II
Dynamic control of gene expression is crucial for most aspects of cell physiology and at its core is RNA polymerase II (RNAPII). Using 53 RNAPII point mutants, we generated a point mutant epistatic miniarray profile (pE-MAP) comprising ~60,000 quantitative genetic interactions in Saccharomyces cere...
ORGANISM(S): Saccharomyces cerevisiae 
2013-08-06 | E-GEOD-47429 | biostudies-arrayexpress
ProteomicsA SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Purposing
An outbreak of the novel coronavirus SARS-CoV-2, the causative agent of COVID-19 respiratory disease, has infected over 170,000 people since the end of 2019, killed over 7,400, and caused worldwide social and economic disruption. SARS-CoV-2 infection has a mortality rate of 3.4% among confirmed case...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 (ncbitaxon:2697049) Homo Sapiens (ncbitaxon:9606) 
2020-03-24 | MSV000085144 | MassIVE
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