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Proteomics2D-PAGE coupled with nLC-MS/MS-based identification of differentialy expressed proteins and tumorigenic pathways in MCF7 breast cancer cell line transfected for JTB protein silencing
Identification of new cancer-associated genes/proteins, characterization of their expression vari-ation, the interactomics-based assessment of differentially expressed genes/proteins (DEGs/DEPs), and understanding the tumorigenic pathways and biological processes involved in BC genesis and progressi...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD046265 | Pride
Breast cancer (bc)  mcf7  jtb protein silencing  overexpressed jtb-interactome  downregulated jtb-interactome  tumorigenic pathways 
TranscriptomicsThe tumor suppressor gene rap1GAP is silenced by mir-101-mediated EZH2 overexpression in invasive squamous cell carcinoma
Rap1GAP is a critical tumor suppressor gene that is down-regulated in multiple aggressive cancers such as head and neck squamous cell carcinoma, melanoma and pancreatic cancer. However, the mechanistic basis of rap1GAP down-regulation in cancers is poorly understood. By employing an integrative appr...
ORGANISM(S): Homo sapiens 
2011-11-02 | E-GEOD-28501 | biostudies-arrayexpress
TranscriptomicsmiRNA Expression In Maintenance and Differentiation of Human Embryonic Stem Cells
Recent advances in the study of human embryonic stem cells (hESCs) and induced-pluripotent stem cells (iPS) highlight their importance as both model systems for basic research and avenues for therapeutic applications. To gain better insight into these cells, a clearer understanding of their molecul...
ORGANISM(S): Homo sapiens 
2010-09-09 | E-GEOD-14473 | biostudies-arrayexpress
UnknownA prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study.
Not available
S-EPMC8576477 | biostudies-literature
UnknownAcute Cardiac Care 2012
Not available
S-EPMC3760571 | biostudies-literature
UnknownA first update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC9352569 | biostudies-literature
UnknownWhole-genome sequencing reveals host factors underlying critical COVID-19.
Not available
S-EPMC9259496 | biostudies-literature
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