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An unexplored consequence of epigenetic alterations associated with cancer is the ectopic expression of tissue-restricted genes. Here, a new strategy was developed to decipher genome-wide expression data in search for these “off-context” gene activations, which consisted first, in identifying a larg...
ORGANISM(S): Homo sapiens 
Fernandez-Cuesta et al, 2014, Nature Communication, Whole exome sequencing data set
Fernandez-Cuesta et al., 2014, Nature Communication, Whole genome sequencing was performed using a read length of 2x100 bp for all samples. On average, 110 Gb of sequence were produced per sample, aiming a mean coverage of 30x for both tumour and matched normal.
SNP 6.0 arrays of carcinoid samples
Fernandez-Cuesta et al, 2014, Nature Communication, RNA Sequencing data set
Pulmonary carcinoids are rare neuroendocrine tumours of the lung. The molecular alterations underlying the pathogenesis of these tumours have not been systematically studied so far. Here we perform gene copy number analysis (n¼54), genome/exome (n¼44) and transcriptome (n¼69) sequencing of pulmonary...
Data Access Committee EGAC00001000064
SCLC - Whole genome sequencing data Publication Peifer et al., 2012, Nature Genetics
SCLC - RNA sequencing data Publication Peifer et al., 2012, Nature Genetics
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