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TranscriptomicsNeurofibromin (Nf1) is required for skeletal muscle development
Neurofibromatosis type 1 (NF1) is a multi-system disease caused by mutations in the NF1 gene encoding a Ras-GAP protein, neurofibromin, which negatively regulates Ras signalling. Besides neuroectodermal malformations and tumours, the skeletal system is often affected (e.g. scoliosis and long bone dy...
ORGANISM(S): Mus musculus 
2011-05-18 | E-GEOD-29343 | biostudies-arrayexpress
ProteomicsOptimized liquid and gas phase fractionations increase HLA-peptidome coverage for primary cell and tissue samples
Mass spectrometry is the most effective method to directly identify peptides presented on HLA molecules. However, current standard approaches often require billions of cells for input material to achieve high coverage of the immunopeptidome and are therefore not compatible with the often limiting am...
ORGANISM(S): Homo Sapiens 
2021-08-30 | PXD027165 | panorama
TranscriptomicsInhibiting Monoacylglycerol Acyltransferase 1 Ameliorates Hepatic Metabolic Abnormalities, but not Inflammation and Injury in Mice
Abnormalities in hepatic lipid metabolism are believed to play a critical role in the etiology of nonalcoholic steatohepatitis (NASH). Monoacylglycerol acyltransferase (MGAT) enzymes convert monoacylglycerol to diacylglycerol, which is the penultimate step in one pathway for triacylglycerol (TAG) sy...
ORGANISM(S): Mus musculus 
2014-11-05 | E-GEOD-60349 | biostudies-arrayexpress
UnknownLGR5 expressing skin fibroblasts define a major cellular hub perturbed in scleroderma.
Not available
S-EPMC7612792 | biostudies-literature
UnknownReporting guidelines for human microbiome research: the STORMS checklist.
Not available
S-EPMC9105086 | biostudies-literature
UnknownDiving into the vertical dimension of elasmobranch movement ecology.
Not available
S-EPMC9390984 | biostudies-literature
UnknownA second update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC10482689 | biostudies-literature
UnknownThe major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
Not available
S-EPMC3235490 | biostudies-literature
UnknownMetformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol.
Not available
S-EPMC12303861 | biostudies-literature
UnknownWhole-brain annotation and multi-connectome cell typing of Drosophila.
Not available
S-EPMC11446831 | biostudies-literature
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