Sort   by:  
 Page size 
TranscriptomicsRNA-seq of the human breast cancer ERα-suppressed MCF-7(MCF-7/SP10+) cells and of their internal control MCF-7 (MCF-7/C) cells
Estrogens receptor a (ERα) is essential for breast tumors,since about seventy percent of breast cancers are detected as ERα positive.Recent studies suggest that ERα is related with the epithelial cell morphology. Recently, it has demonstrated that the suppression of ERα induced epithelial-mesenc...
ORGANISM(S): Homo sapiens 
2018-10-22 | E-MTAB-5537 | biostudies-arrayexpress
GenomicsHypoxa-actived XBP1s recruits HDAC2-EZH2 to engage epigenetic suppression of DNp63 expression and promotes breast cacner metastasis independent HIF1a
Hypoxa-actived XBP1s recruits HDAC2-EZH2 to engage epigenetic suppression of DNp63 expression and promotes breast cacner metastasis independent HIF1a
PRJNA1067530 | ENA
ProteomicsDiscovery and pharmacological evaluation of STEAP4 as a novel target for HER2 overexpressing Breast cancer
The HER2 overexpressing and the Triple Negative Breast Cancer forms (TNBC) remain the most aggressive subtypes of BC with poor prognosis, frequent disease relapse and metastasis. In this study the aim was to identify key membrane-associated proteins which are overexpressed in these aggressive BC sub...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD021819 | Pride
Breast cacner Therapeutic targets Human Steap4 Orbitrap Her2 
GenomicsHypoxa-actived XBP1s recruits HDAC2-EZH2 to engage epigenetic suppression of DNp63 expression and promotes breast cacner metastasis independent HIF1a
Hypoxia is a hallmark of cancer development. However, the molecular mechanisms by which hypoxia promotes tumor metastasis are not fully understood. In this study, we demonstrate that hypoxia promotes breast cancer metastasis through suppression of ΔNp63α-dependent in a HIF1α-independent manner. We s...
ORGANISM(S): Homo sapiens 
2024-01-24 | GSE253833 | GEO
TranscriptomicsRB-loss determines selective resistance and novel vulnerabilities in breast cancer modelsRB loss
The retinoblastoma tumor suppressor (RB1) plays a critical role in coordinating multiple pathways that impact on tumor initiation, disease progression, and therapeutic responses. Here we interrogated the effect of CDK4/6 inhibitor in combination with mTOR inhibtor. Also, we interrogtaed the efffect ...
ORGANISM(S): Homo sapiens 
2021-08-31 | GSE182631 | GEO
GenomicsRNA-seq of the human breast cancer ERα-suppressed MCF-7(MCF-7/SP10+) cells and of their internal control MCF-7 (MCF-7/C) cells
RNA-seq of the human breast cancer ERα-suppressed MCF-7(MCF-7/SP10+) cells and of their internal control MCF-7 (MCF-7/C) cells
PRJEB19767 | ENA
GenomicsRB-loss determines selective resistance and novel vulnerabilities in breast cancer modelsRB loss
RB-loss determines selective resistance and novel vulnerabilities in breast cancer modelsRB loss
PRJNA757134 | ENA
ProteomicsA sub-optimal protein precipitation method to improve identification of low molecular weight less abundant proteins
Mass spectrometry-based proteomics studies have enabled identification and quantification of thousands of proteins from biological samples. High molecular weight abundant proteins are readily sampled in global proteomics studies compared to low molecular weight less abundant proteins. Although exten...
ORGANISM(S): Homo sapiens (Human) 
2021-08-19 | PXD023648 | Pride
Small protein Serum Low molecular weight protein Breast cacner cell line Tumour Protein precipitation 
Sort   by:  
 Page size