Sort   by:  
 Page size 
MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
TranscriptomicsTranscription profiling of human CD4CD45RO T-cells stimulated with interleukin-2, interleukin-6 or TNF-alpha and harvested at 24, 72 or 144 hours or stimulated with anti-CD3 antibodies and harvested at 24 hours
Blood taken from a healthy human donor was used to isolate CD4CD45RO T-cells. Purified cells were stimulated with either interleukin-2 (IL-2), Interleukin-6 (IL-6) and TNF-alpha and harvested at 24 hours, 72 hours (3 days) and 144 hours (6 days) or anti-CD3 antibodies and harvested at 24 hours. Thes...
ORGANISM(S): Homo sapiens 
2008-06-01 | E-MIMR-341 | biostudies-arrayexpress
ProteomicsAn unconventional integrin promotes human immunityAn unconventional integrin promotes human immunity
Cancer remains one of the leading causes of mortality worldwide, with increasing public health interest towards immunological-based approach in disease treatments. Enrichment of certain cell population, namely the CD103+ tissue-resident memory T (Trm) cells has been associated with better clinical p...
ORGANISM(S): Homo sapiens (Human) 
2024-07-30 | PXD045989 | Pride
Human Cancer immunology Interactomics 
UnknownNKG7 Enhances CD8+ T Cell Synapse Efficiency to Limit Inflammation.
Not available
S-EPMC9299089 | biostudies-literature
UnknownProliferation and interleukin 5 production by CD8hi CD57+ T cells.
Not available
S-EPMC2843081 | biostudies-literature
UnknownTranscriptional insights into the CD8(+) T cell response to infection and memory T cell formation.
Not available
S-EPMC3689652 | biostudies-literature
UnknownResistance to regulatory T cell-mediated suppression in rheumatoid arthritis can be bypassed by ectopic foxp3 expression in pathogenic synovial T cells.
Not available
S-EPMC3189031 | biostudies-literature
UnknownT cells discriminate between groups C1 and C2 HLA-C.
Not available
S-EPMC9177145 | biostudies-literature
UnknownLung influenza virus-specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells.
Not available
S-EPMC11464401 | biostudies-literature
UnknowniNKT cell cytotoxic responses control T-lymphoma growth in vitro and in vivo .
Not available
S-EPMC3927984 | biostudies-literature
Sort   by:  
 Page size