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To characterize the subclonal genomic architecture of non-androgen-deprived metastatic prostate cancer, we performed whole-genome sequencing (WGS) of pelvic lymph node metastases and matching noncancerous blood from 10 patients to an average sequencing depth of 55x. The patients are part of PELICAN ...
Aligned Sequence (bam format), Duplicates removed
Raw sequence data, fastq format
Herein we describe a molecular portrait of potentially curable, Gleason 7 and intermediate risk prostate cancer based on genome-wide CNV profiles of 96 patients, and subsequent whole-genome sequencing of 28 tumours from 10 patients, using DNA quantities that are achievable in diagnostic biopsies (50...
To characterize the subclonal genomic architecture of androgen-deprived metastatic prostate cancer, we performed whole-genome sequencing (WGS) of 51 tumours from 10 patients to an average sequencing depth of 55x, including multiple metastases from different anatomic sites in each patient and, in fiv...
single nucleotide variant calls from somatic sniper, vcf format. input for subclonal reconstruction
Aligned sequence data from 14 Prostate cancer samples with BRCA2 mutations
Raw Array data from the CPCGene BRCA study
single nucleotide variant calls from somatic sniper, vcf format
structural variant calls from Delly, vcf format
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