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ProteomicsProteomic profile of human CHME3 microglia in response to the miR-124-3p modulation in Swedish neuronal cells
We aim to evaluate how the levels of miR-124 in APPSwedish neuronal change the signature of interferon-gamma-stimulated human microglia, in a co-culture system. We want to fing possible pathways involved in cell-to-cell signaling and traficking, as well as inflammation-associated and miRNA targets i...
ORGANISM(S): Homo sapiens (Human) 
2022-06-02 | PXD030315 | Pride
Neuron-microglia crosstalk  mirna intercellular signaling  neuroimmune function  vesicular traficking 
ProteomicsmiR-146 modulation in ALS astrocytes
Regarding astrocytes and microglia, we are looking for pathways related with inflammatory activation, phagocytosis and vesicular/exosome trafficking. Regarding motor neurons, we are searching for pathways related with mitochondrial dynamics, Endoplasmic Reticulum stress, cell death, axonal transport...
ORGANISM(S): Mus musculus (Mouse) 
2021-04-06 | PXD024294 | Pride
Als  mir-146a  astrcoyte  motor neuron  microglia 
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