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ProteomicsMicroenvironment remodeling during human iPSC-derived NSC 3D differentiation
Brain microenvironment plays an important role in neurodevelopment and function, where extracellular matrix (ECM) components and soluble factors modulate cellular features, as migration, proliferation survival and neuronal function. Disruption of microenvironment’s homeostasis is often related to pa...
ORGANISM(S): Homo sapiens (Human) 
2018-07-31 | PXD007130 | Pride
3d cultures  neual differentiation  hipsc-derived nsc  ecm  microenvironment  swath 
GenomicsEGAS00001000367-sc-20130612 - samples
In order to progress human induced pluripotent stem cells (hiPSCs) towards the clinic, several outstanding questions must be addressed. It is possible to reprogram different somatic cell types into hiPSCs and from studies in the mouse, it appears that an epigenetic memory of the starting cell type ...
EGAD00001000604 | EGA
GenomicsAssessment of genetic and epigenetic variation in human IPS cells RNA
In order to progress human induced pluripotent stem cells (hiPSCs) towards the clinic, several outstanding questions must be addressed. It is possible to reprogram different somatic cell types into hiPSCs and from studies in the mouse, it appears that an epigenetic memory of the starting cell type ...
EGAS00001000367 | EGA
UnknownEffect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial.
Not available
S-EPMC12124691 | biostudies-literature
Genomics90f6b7fe-358f-45aa-a47d-751fd5536162 - samples
Whole-genome sequencing BAM files of a census-based elderly cohort of Brazilians (n=1171)
EGAD00001008640 | EGA
Genomics>SABE_1171_WGS_GVCF_IDX - samples
Description not provided
EGAD00001008203 | EGA
GenomicsWhole-genome sequencing of a census-based elderly cohort of Brazilians
This project generated a high-coverage WGS dataset of 1,000+ highly admixed elderly from a census-based cohort from São Paulo, Brazil (SABE Study). Current Brazilian population results from admixture of Iberian Europeans, West and East Africans and Native Americans, and from 19th century onwards ...
EGAS00001005052 | EGA
GenomicsSABE Brazil Genomics Committee
Data Access Committee EGAC00001002203
EGAC00001002203 | EGA
ProteomicsSARS-CoV-2 infects brain astrocytes of COVID-19 patients and impairs neuronal viability
COVID-19 patients may exhibit neuropsychiatric and neurological symptoms. We found that anxiety and cognitive impairment are manifested by 28-56% of SARS-CoV-2-infected individuals with mild respiratory symptoms and are associated with altered cerebral cortical thickness. Using an independent cohort...
ORGANISM(S): Homo sapiens (Human) 
2022-09-01 | PXD023781 | Pride
Covid-19 Astrocytes Proteomics Sars-cov2 
UnknownGlobal disparities in surgeons' workloads, academic engagement and rest periods: the on-calL shIft fOr geNEral SurgeonS (LIONESS) study.
Not available
S-EPMC11455666 | biostudies-literature
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