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TranscriptomicsExpression profiling of B.subtils SMY wild-type, (p)ppGpp0, M-NM-^TcodY (p)ppGpp0 and guaB- (p)ppGpp0 cells upon amino acid starvation (RHX) or guanosine (Guo) treatment.
The nucleotide (p)ppGpp is crucial for viability during amino acid limitation in bacteria, yet how it accomplishes this remains unknown. We found that the absence of (p)ppGpp in Bacillus subtilis cells leads to multiple amino acid auxotrophy, and that (p)ppGpp allows for prototrophy by reducing GTP ...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2013-11-01 | E-GEOD-41501 | biostudies-arrayexpress
TranscriptomicsExpression profiling of B.subtils SMY wild-type vs. (p)ppGpp0 cells upon amino acid starvation.
Cells constantly adjust their metabolism in response to environmental conditions, yet major mechanisms underlying survival remain poorly understood. We discover a post-transcriptional mechanism that integrates starvation response with GTP homeostasis to allow survival, enacted by the nucleotide (p)p...
ORGANISM(S): Bacillus subtilis 
2012-11-01 | E-GEOD-39758 | biostudies-arrayexpress
UnknownDiagnostic performance of a 5-plex malaria immunoassay in regions co-endemic for Plasmodium falciparum, P. vivax, P. knowlesi, P. malariae and P. ovale.
Not available
S-EPMC9068623 | biostudies-literature
TranscriptomicsThe effects of ibuprofen on the transcriptome of a euryhaline fish
Ibuprofen is one of the most commonly detected pharmaceuticals in wastewater effluent; however the effects of ibuprofen on aquatic organisms are poorly understood. This study presents the transcriptome-wide response of the inland silverside, Menidia beryllina, to chronic 14 d exposures to ibuprofen....
ORGANISM(S): Menidia beryllina 
2015-09-01 | E-GEOD-64967 | biostudies-arrayexpress
TranscriptomicsLactobacillus reuteri ATCC 55730: Before vs after exposure to 0.5% bile.
Transcriptional profiling of Lactobacillus reuteri ATCC 55730 mid-log cultures before vs after exposure to 0.5% bovine bile (oxgall). Two sets of array experiments were performed. One set compared the expression profiles of L. reuteri ATCC 55730 cells before bile exposure vs cells that had been exp...
ORGANISM(S): Lactobacillus reuteri 
2010-05-26 | E-GEOD-10155 | biostudies-arrayexpress
TranscriptomicsSkeletal muscle characteristics of inherited low and high aerobic exercise capacity
Epidemiological studies reveal a strong link between low aerobic capacity and metabolic and cardiovascular diseases. Two-way artificial selection of rats based on low and high intrinsic exercise capacity has produced two strains that also differ in risk for metabolic syndrome (Koch LG, Britton SL. A...
ORGANISM(S): Rattus norvegicus 
2010-04-13 | E-GEOD-17190 | biostudies-arrayexpress
ProteomicsP. falciparum merozoites phoshoproteome
Pathology of the most lethal form of malaria is caused by Plasmodium falciparum asexual blood stages and initiated by merozoite invasion of erythrocytes. We present a phosphoproteome analysis of extracellular merozoites revealing 1765 unique phosphorylation sites including 785 sites not previously d...
ORGANISM(S): Bos taurus (Bovine) Plasmodium falciparum (isolate 3D7) 
2015-04-23 | PXD001684 | Pride
Merozoites  plasmodium falciparum  malaria  phosphorylation 
UnknownVoltammetric Sensor Based on the Poly(p-aminobenzoic Acid) for the Simultaneous Quantification of Aromatic Aldehydes as Markers of Cognac and Brandy Quality.
Not available
S-EPMC9960838 | biostudies-literature
UnknownMolecular modelling and anticholinesterase activity of the essential oil from three chemotypes of Lippia alba (Mill.) N.E.Br. ex Britton & P. Wilson (Verbenaceae).
Not available
S-EPMC11031784 | biostudies-literature
UnknownGene 5 of the avian coronavirus infectious bronchitis virus is not essential for replication.
Not available
S-EPMC1143771 | biostudies-literature
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