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TranscriptomicsComplex regulation of the PEP carboxykinase gene pck and characterization of its GntR-type regulator IolR as a repressor of myo-inositol utilization genes in Corynebacterium glutamicum
DNA affinity chromatography with the promoter region of the Corynebacterium glutamicum pck gene, encoding phosphoenolpyruvate carboxykinase (PEPCk), led to the isolation of four transcriptional regulators, i.e., RamA, GntR1, GntR2 and IolR. Determination of the PEPCk activity of the deletion mutant...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2013-07-29 | E-GEOD-44812 | biostudies-arrayexpress
TranscriptomicsThe Two-component Signal Transduction System CopRS of Corynebacterium glutamicum is Required for Adaptation to Copper-excess Stress
Copper is an essential cofactor for many enzymes but at high concentrations it is toxic for the cell. Copper ion concentrations ≥50 µM inhibited growth of Corynebacterium glutamicum. The transcriptional response to 20 µM Cu2+ was studied using DNA microarrays and revealed 26 genes that showed a ≥3-f...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2011-09-04 | E-GEOD-27510 | biostudies-arrayexpress
TranscriptomicsControl of heme homeostasis in Corynebacterium glutamicum by the two-component system HrrSA
The response regulator HrrA belonging to the HrrSA two-component system (previously named CgtSR11) is known to be repressed by the global iron-dependent regulator DtxR in Corynebacterium glutamicum. Sequence analysis indicated an involvement of the HrrSA system in heme-dependent gene expression. Gro...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2010-12-17 | E-GEOD-26122 | biostudies-arrayexpress
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