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UnknownCombination of AID2 and BromoTag expands the utility of degron-based protein knockdowns.
Not available
S-EPMC11387839 | biostudies-literature
UnknownDevelopment of BromoTag: A "Bump-and-Hole"-PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins.
Not available
S-EPMC8558867 | biostudies-literature
UnknownCombination of AID2 and BromoTag expands the utility of degron-based protein knockdowns
Not available
S-SCDT-10_1038-S44319-024-00224-4 | biostudies-other
UnknownTargeted dephosphorylation of SMAD3 as an approach to impede TGF-β signaling.
Not available
S-EPMC11298613 | biostudies-literature
TranscriptomicsDegron models: a toolbox for rapid in vivo depletion of essential proteins regulating mRNA metabolism
Due to their essentiality, studying proteins involved in fundamental processes in vivo is challenging. PROTAC-based systems offer time-controlled protein depletion, but their characterization in vivo remains limited. Here, with an efficient direct zygote editing protocol, we generated degron-tag mod...
ORGANISM(S): Mus musculus 
2026-02-23 | GSE309776 | GEO
UnknownTargeted dephosphorylation of TFEB promotes its nuclear translocation.
Not available
S-EPMC11284556 | biostudies-literature
ProteomicsTargeted dephosphorylation of TFEB promotes its nuclear translocation
Reversible phosphorylation of the transcription factor EB (TFEB) coordinates cellular responses to metabolic and other stresses. During nutrient replete and stressor-free conditions, phosphorylated TFEB is primarily localised to the cytoplasm. Stressor-mediated reduction of TFEB phosphorylation prom...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD053311 | Pride
Adphosphotase Dephosphorylation Bdpic Ppp2ca Tfeb Phostac 
ProteomicsTargeted dephosphorylation of TFEB promotes its nuclear translocation
Reversible phosphorylation of the transcription factor EB (TFEB) coordinates cellular responses to metabolic and other stresses. During nutrient replete and stressor-free conditions, phosphorylated TFEB is primarily localised to the cytoplasm. Stressor-mediated reduction of TFEB phosphorylation prom...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD053308 | Pride
Bdpic Ppp2ca Tfeb Adphosphatase Phostac 
ProteomicsDegron models: a toolbox for rapid in vivo depletion of essential proteins regulating mRNA metabolism
Due to their essentiality, studying proteins involved in fundamental processes in vivo is challenging. PROTAC-based systems offer time-controlled protein depletion, but their characterization in vivo remains limited. Here, with an efficient direct zygote editing protocol, we generated degron-tag mod...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-26 | PXD069282 | Pride
Tmt Degron-tag Liver Mouse 
UnknownCorrection to "Development of BromoTag: A "Bump-and-Hole"-PROTAC System To Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins".
Not available
S-EPMC11831586 | biostudies-literature
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