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MetabolomicsFasting wildtype, tfeb -/- knockout, and lmna -/- knockout metabolite profiling of adult zebrafish
Not available
ORGANISM(S): Danio rerio 
ST000584 | MetabolomicsWorkbench
ProteomicsTFEB Immunoprecipitation And Proteome
Our studies in Salmonella Typhimurium (S. Typhimurium)-infected cells indicate that TFEB has a non-transcriptional, cytosolic function in addition to its well-characterized role as a transcription factor in regulating autophagy and lysosome biogenesis. An unbiased proteomics approach revealed that T...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD013758 | Pride
Ip Proteome Tfeb Lc-ms/ms 
TranscriptomicsIdentification of Tfeb-dependent genes downstream of mTORC1 in MEFs
Mammalian target of rapamycin (mTOR) complex 1 (mTORC1) is a critical regulator of cell growth by integrating multiple signals (nutrients, growth factors, energy and stress) and is frequently deregulated in many types of cancer. We used a robust experimental paradigm involving the combination of two...
ORGANISM(S): Mus musculus 
2011-08-02 | E-GEOD-28021 | biostudies-arrayexpress
TranscriptomicsAMPK governs lineage specification through Tfeb-dependent regulation of lysosomes
Faithful execution of developmental programs relies on the acquisition of unique cell identities from pluripotent progenitors, a process governed by combinatorial inputs from numerous signaling cascades that ultimately dictate lineage-specific transcriptional outputs. Despite growing evidence that m...
ORGANISM(S): Mus musculus 
2016-03-09 | E-GEOD-77705 | biostudies-arrayexpress
ProteomicsLactylation stabilizes TFEB to elevate autophagy and lysosomal activity
To identify the interaction proteins of TFEB, HEK293T cells transiently expressing TFEB-Flag were immunoprecipitated with anti-Flag beads. The beeds were used to do a LC/MS.
ORGANISM(S): Homo Sapiens 
2024-03-13 | PXD050578 |
ProteomicsTargeted dephosphorylation of TFEB promotes its nuclear translocation
Reversible phosphorylation of the transcription factor EB (TFEB) coordinates cellular responses to metabolic and other stresses. During nutrient replete and stressor-free conditions, phosphorylated TFEB is primarily localised to the cytoplasm. Stressor-mediated reduction of TFEB phosphorylation prom...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD053308 | Pride
Bdpic Ppp2ca Tfeb Adphosphatase Phostac 
ProteomicsMS analysis of human TFEB posttranslational modification
Mass spectrometry analysis of TFEB acetylation, phosphorylation, and ubiquitination without or with TSA treatment
ORGANISM(S): Homo Sapiens 
PXD035879 |
ProteomicsTargeted dephosphorylation of TFEB promotes its nuclear translocation
Reversible phosphorylation of the transcription factor EB (TFEB) coordinates cellular responses to metabolic and other stresses. During nutrient replete and stressor-free conditions, phosphorylated TFEB is primarily localised to the cytoplasm. Stressor-mediated reduction of TFEB phosphorylation prom...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD053311 | Pride
Adphosphotase Dephosphorylation Bdpic Ppp2ca Tfeb Phostac 
ProteomicsdiGly ubiquitin remnant profiling upon TFEB overexpression
We performed proteomic analysis of di-Gly peptides to identify which proteins are ubiquitinated in cells overexpressing TFEB compared to non-expressing cells.
ORGANISM(S): Homo sapiens (Human) 
2025-11-18 | PXD065497 | Pride
Ubiquitin Digly Tfeb Hela 
TranscriptomicsProfiling gene expression in HeLa cells following TFEB transient transfection
Total RNA samples from three biological replicates in which TFEB was transiently overexpressed in HeLa cells by transfection using a pcDNA3 vector. As negative control, we used total RNA samples from HeLa cells transfected with an empty pcDNA3 vector. TFEB transfection
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-16267 | biostudies-arrayexpress
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