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MetabolomicsA Prototypic Small Molecule Database for Bronchoalveolar Lavage-Based Metabolomics
The analysis of bronchoalveolar lavage fluid (BALF) using mass spectrometry-based metabolomics can provide insight into lung diseases, such as asthma. However, the important step of compound identification is hindered by the lack of a small molecule database that is specific for BALF. Here we descri...
2018-02-09 | MTBLS591 | MetaboLights
TranscriptomicsscRNA-seq analysis of cell subpopulations of the bronchoalveolar lavage fluid of healthy dogs
In dogs, a species for which markers of cell populations are often limiting, we sought to evaluate in an unbiased way the heterogeneity of cell subpopulations in the bronchoalveolar lavage fluid of healthy dogs, by single-cell RNA-sequencing.
ORGANISM(S): Canis lupus familiaris 
2020-06-29 | E-MTAB-9265 | biostudies-arrayexpress
MetabolomicsLipid mediators of inflammation in BALF 6-19 days after infection with influenza
In this study broncho-alveolar lavage fluid (BALF) from mice infected with influenza A virus, PR8 (280 PFU) was analyzed for lipidomic host response in comparison with the mock infected animals. Time Points: 6, 9, 11, 13 and 19 days post infection, done in 8-10 replicates.)
2013-05-30 | MTBLS32 | MetaboLights
MetabolomicsLipid mediators of inflammation in BALF 3-13 days after infection with influenza
In this study broncho-alveolar lavage fluid (BALF) from mice infected with influenza A virus, PR8 (200 PFU) or X31 (200,000 PFU) was analyzed for lipidomic host response in comparison with the mock infected animals. Time Points: 3, 5, 6, 7, 9, 10 and 13 days post infection.)
2013-05-30 | MTBLS34 | MetaboLights
MetabolomicsLipid mediators of inflammation in BALF 3-19 days after infection with influenza
In this study broncho-alveolar lavage fluid (BALF) from mice infected with influenza A virus, PR8 (200 PFU and 200,000 PFU), X31 (2000,000 PFU) was analyzed for lipidomic host response in comparison with the mock infected animals. Time Points: 3, 5, 7, 9, 11, 13, 19 days post infection, done in 8-10...
2013-05-09 | MTBLS31 | MetaboLights
MetabolomicsLipid mediators of inflammation in BALF 3-11 days after infection with influenza
Bioactive lipid mediators play a crucial role in the induction and resolution of inflammation. To elucidate their involvement during influenza infection, liquid chromatography/mass spectrometry lipidomic profiling of 141 lipid species was performed on a mouse influenza model using two viruses of sig...
2013-05-30 | MTBLS33 | MetaboLights
MetabolomicsMulti-0mics and Machine Learning-Based Profiling of Severity signatures in Mycoplasma Pneumoniae Infection in children

Mycoplasma pneumoniae pneumonia (MPP) is a common respiratory infection in children. Yet the mechanisms driving its progression to severe disease remain poorly understood. This study employs a comprehensive proteomic and metabolomic approach to elucidate severity-related pathways and identify pot...

2026-01-04 | MTBLS13511 | MetaboLights
ProteomicsQuantitative proteomic analysis of bronchoalveolar lavage fluid in West Highland white terriers with canine idiopathic pulmonary fibrosis C4PR_LIV
Canine idiopathic pulmonary fibrosis (CIPF) is a chronic, progressive, interstitial fibrosing lung disease, manifesting as cough, exercise intolerance and ultimately, dyspnea and respiratory failure. It mainly affects West Highland white terriers (WHWTs), lacks curable treatment and has a poor progn...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2022-05-20 | PXD028916 | Pride
Bronchoalveolar lavage fluid  canine  reflux aspiration  proteomics: west highland white terrier 
ProteomicsStandardized Sample Preparation of Paediatric Bronchoalveolar Lavage Fluid for Mass Spectrometry-based Proteomic Analysis
This study establishes a standardized and reproducible workflow for LC-MS/MS-based proteomic analysis of paediatric bronchoalveolar lavage fluid (BALF). Using minimal sample volumes, we systematically compared preparation strategies and identified a simplified protocol that maximizes protein recover...
ORGANISM(S): Homo sapiens (Human) 
2025-11-21 | PXD067840 | Pride
Paediatric bronchoalveolar lavage fluid  balf  proteomics  lc-ms/ms  sample preparation  orbitrap fusion lumos  biomarker discovery  respiratory disease 
MetabolomicsValidation: Multi-Omics and Machine Learning-Based Profiling of Severity Signatures in Mycoplasma Pneumoniae Infection in Children

Mycoplasma pneumoniae pneumonia (MPP) is a common respiratory infection in children, yet the mechanisms driving its progression to severe disease remain poorly understood. This study employs a comprehensive proteomic and metabolomic approach to elucidate severity-related pathways and identify pot...

2026-01-05 | MTBLS13504 | MetaboLights
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