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UnknownALDH1A3 loss of function causes bilateral anophthalmia/microphthalmia and hypoplasia of the optic nerve and optic chiasm.
Not available
S-EPMC3723310 | biostudies-literature
TranscriptomicsTranscriptomic responses of Atlantic salmon (Salmo salar) to environmental enrichment during juvenile rearing
Captive rearing programs (hatcheries) are often used in conservation and management efforts for at-risk salmonid fish populations. However, hatcheries typically rear juveniles in environments that contrast starkly with natural conditions, which may lead to phenotypic and/or genetic changes that adve...
ORGANISM(S): Salmo salar 
2014-12-10 | E-GEOD-63982 | biostudies-arrayexpress
TranscriptomicsMapping of cohesion factor association sites in S. cerevisiae - Meiosis I chromosome segregation is established through regulation of microtubule-kinetochore interactions.
During meiosis, a single round of DNA replication is followed by two consecutive rounds of nuclear divisions called meiosis I and meiosis II. In meiosis I, homologous chromosomes segregate, while sister chromatids remain together. Determining how this unusual chromosome segregation behavior is estab...
ORGANISM(S): Saccharomyces cerevisiae 
2012-10-05 | E-GEOD-41339 | biostudies-arrayexpress
TranscriptomicsExpression data of wild-type and dcl1-15 torpedo-staged embryos
Severe loss-of-function alleles of DCL1 are embryonic lethal. Defects in cell division were seen as early as the globular stage in the strong loss-of-function allele dcl1-15. Phenotypic work with dcl1-15 and the null allele dcl1-5 suggested that, in addition to the severe patterning defects, the m...
ORGANISM(S): Arabidopsis thaliana 
2011-02-17 | E-GEOD-24887 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Xenopus tropicalis wild type and whitehart embryos
Two batches each of 40 wild type and 40 whitehart sibling embryos were sorted by morphological criteria at stage 37-38, RNA prepped and hybed to arrays. With mutant versus wild type sibling pools. Dyeswaps were performed.
ORGANISM(S): Xenopus tropicalis 
2022-11-21 | E-MEXP-691 | biostudies-arrayexpress
GenomicsChromatin Immunoprecipitation of TRA-1 in C. elegans and C. briggsae
The goal of this study is to identify and characterize sites in the C. elegans genome bound by the transcription factor TRA-1. TRA-1 ChIP-seq was performed in the following stages of animals in duplicate: 1) L2 stage of C. elegans wild-type N2 strain; 2) L3 stage of C. elegans wild-type N2 strain; 3...
ORGANISM(S): Caenorhabditis briggsae 
2013-11-04 | E-GEOD-48917 | biostudies-arrayexpress
TranscriptomicsTranscriptome partitioning in mouse fertilization.
RNA transcripts are distributed non-uniformly in the oocytes of many animals, such that newly-divided embryo cells (blastomeres) inherit distinct transcriptomes following fertilization. In animals such as the frog, Xenopus laevis, programmed transcript regionalization directs early embryonic axis fo...
ORGANISM(S): Mus musculus 
2011-04-21 | E-GEOD-27396 | biostudies-arrayexpress
ProteomicsGeotraces EPZT
Surface seawater ENV solid phase extraction samples collected on the US GEOTRACES EPZT cruise (October-December 2013).
ORGANISM(S): Environmental Samples <bacillariophyta> (ncbitaxon:33858) 
MSV000080173 | MassIVE
GenomicsMayo-Perlegen LEAPS (Linked Efforts to Accelerate Parkinson's Solutions) Collaboration

We performed a two-tiered, whole-genome association study of Parkinson disease (PD). For tier 1, we individually genotyped 198,345 uniformly spaced and informative single-nucleotide polymorphisms (SNPs) in 443 sibling pairs discordant for PD. For tier 2a, we individually genotyped 1,793 PD-asso...

phs000048.v1.p1 | EGA
GenomicsMulti-Ethnic Study of Atherosclerosis (MESA) Cohort

MESA
The Multi-Ethnic Study of Atherosclerosis (MESA) is a study of the characteristics of subclinical cardiovascular disease (disease detected non-invasively before it has produced clinical signs and symptoms) and the risk factors that predict progression to clinically overt cardiova...

phs000209.v10.p2 | EGA
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