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TranscriptomicsAspartoacylase-dependent transcriptome changes in immortalized brown adipocytes
Here we investigated the effect of stable knock-down of the NAA-catabolizing enzyme, Aspartoacylase (Aspa), on global gene expression in a brown adipocyte cell line. Immortalized brown adipogenic cells (iBACs) with stable Aspa knock-down and control cells were grown until confluence and then differe...
ORGANISM(S): Mus musculus 
2016-02-29 | E-GEOD-65906 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse white adipose tissue and brown adipose tissue from Bscl2 knock-out mice and their wild-type control mice
Experiments were designed to compare white adipose tissue (WAT) or brown adipose tissue (BAT) -in male and female mice- between Bscl2 knock-out mice and their wild-type control mice. RNA was pooled to obtain 2x 8µg per tissue source and subjected to dye-swap hybridization.
ORGANISM(S): Mus musculus 
2010-06-09 | E-MARS-18 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling of the Retina after Transcorneal Electrical Stimulation in Wildtype Brown Norway Rats
Purpose: To investigate the effect of transcorneal electrical stimulation (TES) on the retina of wildtype Brown Norway (BN) rats by gene expression profiling. Methods: TES was applied to BN adult wildtype rat retina in vivo for 1h (1ms biphasic pulses at 20Hz; current: 200 M-BM-5A). RNA was isolated...
ORGANISM(S): Rattus norvegicus 
2011-11-21 | E-GEOD-26174 | biostudies-arrayexpress
TranscriptomicsMitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
BAT transcriptome from control and brown adipocyte-specific Rev-erbα/β double knockout mice housed at thermoneutrality or cold-challenged for 6 hours. Brown adipose tissue (BAT) samples were collected from control and brown adipocyte-specific Rev-erbα/β double knockout mice (Ucp1-Cre; Nr1d1/2 fl/fl)...
ORGANISM(S): Mus musculus 
2026-09-23 | E-MTAB-17580 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila female whole bodies treated with juvenile hormone
Juvenile hormone (JH) and 20-hydroxy-ecdysone (20E) are highly versatile hormones, coordinating development, growth, and reproduction in insects. Pulses of 20E provide key signals for initiating developmental and physiological transitions, while JH promotes or inhibits these signals in a stage-speci...
ORGANISM(S): Drosophila melanogaster 
2008-06-16 | E-GEOD-9001 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of six tissues from ATGL knock-out versus wild type mice
Gene expression profiling in 6 tissues (white adipose tissue (WAT), brown adipose tissue (BAT), cardiac muscle (CM), liver (LIV), kidney (KID), skeletal muscle (SM)) from ATGL(-/-) mice versus wildtype (ATGL+/+) mice.
ORGANISM(S): Mus musculus 
2008-02-03 | E-MARS-8 | biostudies-arrayexpress
ProteomicsHigh-throughput identification of RNA localization elements reveals a regulatory role for A/G rich sequences
This experiment aims to identify the RNA-binding proteome that is pulled-down from a cellular lysate with biotinylated RNA probes.
ORGANISM(S): Mus musculus (Mouse) 
2022-09-21 | PXD030720 | Pride
Lc-ms/ms 
TranscriptomicsMitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
Transcriptome from immortalized murine brown adipocytes BMC. Cells were transfected with siRNA construct #1 or construct #2 (pool) or non-targeting control on day 3 of differentiation and harvested on day 7 of differentiation.
ORGANISM(S): Mus musculus 
2026-09-23 | E-MTAB-17577 | biostudies-arrayexpress
UnknownBrown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis
Not available
S-SCDT-10_1038-S44318-023-00008-X | biostudies-other
TranscriptomicsTranscription profiling of human immunoglobulin mutation genotype in B Cell chronic lymphocytic leukaemia
The Journal of Experimental Medicine, Volume 194, Number 11, December 3, 2001 1639-1648 Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia Andreas Rosenwald1, Ash A. Alizadeh2, George Widhopf5, Richard Simon6, R. Eric Davis1, Xin Yu1, ...
ORGANISM(S): Homo sapiens 
2005-06-29 | E-SMDB-1002 | biostudies-arrayexpress
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