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TranscriptomicsTranscription profiling of brain, liver and spleen from rats infected with Escherichia coli K1 and treated with capsule-selective endosialidase E
Transcription profiling of infected and treated (Capsule-Selective Endosialidase E Minimizes) of RNA isolated from brain/spleen/liver of rats with E.coli K1
ORGANISM(S): Rattus norvegicus 
2010-01-10 | E-MEXP-2406 | biostudies-arrayexpress
TranscriptomicsBiological Aging and Circadian Mechanisms in Murine Brown Adipose Tissue, Inguinal White Adipose Tissue, and Liver (Nov 2009 dataset)
The circadian profile of the transcriptomes in murine tissues was compared between groups of young and old male mice. The oscillatory phase and absolute expression levels were evaluated as a function of biological age. Distinct differences in multiple pathways were apparent based on biological and c...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-25323 | biostudies-arrayexpress
TranscriptomicsBiological Aging and Circadian Mechanisms in Murine Brown Adipose Tissue, Inguinal White Adipose Tissue, and Liver (Jan 2010 dataset)
The circadian profile of the transcriptomes in murine tissues was compared between groups of young and old male mice. The oscillatory phase and absolute expression levels were evaluated as a function of biological age. Distinct differences in multiple pathways were apparent based on biological and c...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-25324 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiles of wild brown trout chronically exposed to metals using RNA-seq in a Illumina GAII platform
To investigate mechanisms of metal tolerance in the gill, gut, kidney and liver of brown trout inhabiting the river Hayle (highly metal contaminated) compared with a control population from the river Teign. mRNA samples were sequenced (Illumina GAII) from a pooled embryonic sample and 12 multiplexed...
ORGANISM(S): Salmo trutta 
2014-06-01 | E-GEOD-45637 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling of the Retina after Transcorneal Electrical Stimulation in Wildtype Brown Norway Rats
Purpose: To investigate the effect of transcorneal electrical stimulation (TES) on the retina of wildtype Brown Norway (BN) rats by gene expression profiling. Methods: TES was applied to BN adult wildtype rat retina in vivo for 1h (1ms biphasic pulses at 20Hz; current: 200 M-BM-5A). RNA was isolated...
ORGANISM(S): Rattus norvegicus 
2011-11-21 | E-GEOD-26174 | biostudies-arrayexpress
TranscriptomicsTranscript profiles of juvenile female brown trout exposed to glyphosate and Roundup herbicides.
This study aimed to investigate the hepatic transcriptional response of brown trout to glyphosate, and its formulated product, Roundup. We exposed juvenile female brown trout to three concentrations of glyphosate (0.01, 0.5 and 10 mg/L) and Roundup (0.01, 0.5 and 10 mg/L glyphosate acid equivalent) ...
ORGANISM(S): Salmo trutta 
2015-04-16 | E-GEOD-56855 | biostudies-arrayexpress
TranscriptomicsOverlapping and unique responses of E. coli to adverse conditions
In the present study we have determined the global gene expression and biomolecular composition in an Escherichia coli model strain exposed to ten adverse conditions (sodium chloride, ethanol, glycerol, two acids (hydrochloric acid and acetic acid), sodium hydroxide, heat (46°C) and cold (15°C) as...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2010-05-18 | E-GEOD-11041 | biostudies-arrayexpress
TranscriptomicsThe Apple Flavonoid Phloretin Inhibits Escherichia coli O157:H7 Biofilm Formation and Ameliorates Colon Inflammation in Rat
Pathogenic biofilms have been associated with persistent infections due to high resistance to antimicrobial agents while commensal biofilms often fortify host immune system. Hence, controlling biofilm formation of both pathogenic bacteria and commensal bacteria is important in bacteria-related dise...
ORGANISM(S): Escherichia coli 
2011-11-22 | E-GEOD-28144 | biostudies-arrayexpress
TranscriptomicsA comparative analysis of genistein and daidzein in affecting lipid metabolism in rat liver
Effects of soy isoflavones, genistein and daidzein, on the hepatic gene expression profile and indices for lipid metabolism were compared in rats. The GeneChip data was normalized and summarized by using SuperNORM data service (Skylight Biotech Inc.). Significance of expressional change among groups...
ORGANISM(S): Rattus norvegicus 
2012-10-10 | E-GEOD-41420 | biostudies-arrayexpress
UnknownReduced Nicotine Cigarettes and E-Cigarettes in High-Risk Populations: 3 Randomized Clinical Trials.
Not available
S-EPMC11380105 | biostudies-literature
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