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UnknownRandomized Open-Label Phase II Trial of Apitolisib (GDC-0980), a Novel Inhibitor of the PI3K/Mammalian Target of Rapamycin Pathway, Versus Everolimus in Patients With Metastatic Renal Cell Carcinoma.
Not available
S-EPMC5569691 | biostudies-literature
UnknownTransferable Immunoglobulin A-Coated Odoribacter splanchnicus in Responders to Fecal Microbiota Transplantation for Ulcerative Colitis Limits Colonic Inflammation.
Not available
S-EPMC8678328 | biostudies-literature
TranscriptomicsTranscription profiling of human optic nerve head (ONH) astrocytes exposed to either 60 mm Hg hydrostatic pressure (HP) or control ambient pressure (CP) to identify HP-responsive genes
Gene expression in human optic nerve head (ONH) astrocytes exposed to either 60 mm Hg hydrostatic pressure (HP) or control ambient pressure (CP) was compared using Affymetrix GeneChip microarrays to identify HP-responsive genes. Primary ONH astrocytes from two male Caucasian donors (passage 4) were ...
ORGANISM(S): Homo sapiens 
2007-09-25 | E-GEOD-758 | biostudies-arrayexpress
UnknownGut bacteria-derived serotonin promotes immune tolerance in early life.
Not available
S-EPMC11328322 | biostudies-literature
UnknownImpact of centre volume, surgeon volume, surgeon experience and geographic location on reoperation after intramedullary nailing of tibial shaft fractures
Not available
S-EPMC8410470 | biostudies-literature
TranscriptomicsCapture-C experiments on auxin treated control (E14-Tir) and Scc1-AID, Ring1b-AID, Ring1b-AID-Scc1-AID and CTCF-AID (with and without a 6-hour auxin treatment) cells
The aim of the experiment was to gain a higher resolution for specific regions of interest to complement the Hi-C results. Capture-C experiments were performed on four-inducible degrons for Scc1, Ringb, Ring1b-Scc1 and CTCF, and Tir1 control, always in triplicates (three biological replicates per co...
ORGANISM(S): Mus musculus 
2020-01-23 | E-MTAB-7840 | biostudies-arrayexpress
UnknownGut microbiota-derived metabolites confer protection against SARS-CoV-2 infection.
Not available
S-EPMC9348133 | biostudies-literature
TranscriptomicsFunction-based discovery of significant transcriptional temporal patterns in insulin-stimulated muscle cells
Background: Insulin's effect on protein synthesis (translation of transcripts) and post-translational modifications, especially those involving reversible modifications such as phosphorylation of various signaling proteins, are extensively studied. On the other hand, insulin's effect on the transcri...
ORGANISM(S): Rattus norvegicus 
2012-05-02 | E-GEOD-28997 | biostudies-arrayexpress
TranscriptomicsSix in situ Hi-C libraries of control and mESC auxin-inducible degrons for Scc1 and Ring1b.
In this experiment, we've examined chromatin conformation differences of E14 mESC against cohesin and Ring1b degrons. We performed a modified in situ Hi-C protocol from (Rao et al., 2014) that can be found in detail at (Díaz et al., 2018). Samples were digested with MboI restriction enzyme. The aim ...
ORGANISM(S): Mus musculus 
2020-01-23 | E-MTAB-7816 | biostudies-arrayexpress
GenomicsRING1B calibrated ChIP-seq (cChIPseq) datasets for control mESCs and an Scc1-AID auxin-inducible degron.
We examined 3D chromatin structure in the absence of cohesin (Scc1-AID auxin-inducible degron) and a control line (E14-Tir1) and found that PRC1 core promoter component RING1B was one of the most enriched proteins. Hence, we performed calibrated ChIP-seq experiments on the control (E14-Tir1) and the...
ORGANISM(S): Mus musculus 
2020-01-23 | E-MTAB-7817 | biostudies-arrayexpress
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