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TranscriptomicsBreastPRS is a Gene Expression Assay that Stratifies Intermediate-Risk Oncotype DX Patients into High or Low-Risk for Disease Recurrence
Molecular prognostic assays, such as Oncotype DX, are increasingly incorporated into the management of patients with invasive breast carcinoma. BreastPRS is a new molecular assay developed and validated from a meta-analysis of publically available genomic datasets. We applied the assay to matched fr...
ORGANISM(S): Homo sapiens 
2013-06-23 | E-GEOD-47109 | biostudies-arrayexpress
UnknownEvaluation of a trauma-informed care (TIC) training program across community health centers in Texas: a qualitative study.
Not available
S-EPMC11545729 | biostudies-literature
TranscriptomicsmRNA Expression data from rats treated with ANIT or vehicle
Adult Sprague Dawley rats were treated i.g. with 50 mg/kg alpha-naphthylisothiocyanate (ANIT) or vehicle (corn oil). Hepatobiliary liver injury occurred at 24 h postdose in ANIT rats with repair at 120h. Livers were extracted from rats at 24h and 120 h post ANIT exposure. This study investigated dif...
ORGANISM(S): Rattus norvegicus 
2015-08-26 | E-GEOD-72387 | biostudies-arrayexpress
TranscriptomicsEffects of two strains of Lactobacillus fermentum on germ free rats
Transcription profiling of intestinal tissue from germ free rats mono-colonised with one of two strains of Lactobacillus fermentum; AGR1485 or AGR 1487 Two colour microarray, reference design. 2 treatments (AGR1485 or AGR1487) and 2 tissues analysed (colon or duodenum): Biological replicates: 6
ORGANISM(S): Rattus norvegicus 
2014-06-25 | E-GEOD-58777 | biostudies-arrayexpress
UnknownAssessing The Capacity Of Local Social Services Agencies To Respond To Referrals From Health Care Providers.
Not available
S-EPMC8336061 | biostudies-literature
TranscriptomicsGene expression profiles induced by overexpression of PDEF in MCF10A mammary epithelial cell line
Recent studies suggest that PDEF is required for secretory cell differentiation in several epithelial tissues. To investigate PDEF in the mammary gland, we examined the effect of this transcription factor on gene expression using microarray based profiling of MCF-10A cells. These cells are non-trans...
ORGANISM(S): Homo sapiens 
2014-03-29 | E-GEOD-40986 | biostudies-arrayexpress
TranscriptomicsPDEF knockdown and overexpression in mammary epithelial cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-03-29 | E-GEOD-40987 | biostudies-arrayexpress
TranscriptomicsGene expression profiles induced by shRNA-mediated knockdown of PDEF in MCF7 mammary epithelial cell line
Microarray gene expression analysis was performed in MCF7 cells transduced with a non-specific shRNA or PDEF-targeting shRNA, and both subjected to hormone depletion for 48 hours. Analyses of differentially expressed genes combined with gene ontology revealed a downregulation of cell cycle related-g...
ORGANISM(S): Homo sapiens 
2014-03-29 | E-GEOD-40985 | biostudies-arrayexpress
ProteomicsDistinct ribosome states trigger diverse mRNA quality control pathways
Key protein adapters couple translation to mRNA decay on specific classes of problematic mRNAs in eukaryotes. Slow decoding on nonoptimal codons leads to codon-optimality-mediated decay (COMD) and prolonged arrest at stall sites leads to no-go decay (NGD). The identities of the decay factors underly...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-08-08 | PXD030076 | Pride
Comd Ngd Syh1 Rna decay Smy2 Codon-optimality-mediated decay No-go decay 
ProteomicsSzewczyk_InhibitionOfPRMT7_P36_2020
This dataset consists of 16 raw MS files, acquired on Orbitrap Fusion Lumos Tribrid mass spectrometer operated in Data Dependent Acquisition (DDA) mode for the 8 input files and DDA with simultaneous parallel reaction monitoring (targeted masses; 599.33, 604.33, 608.23, 606.33, 407.89, 403.22, 651.3...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-08 | MSV000084773 | MassIVE
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