Sort   by:  
 Page size 
GenomicsscRNA seq analysis on immune cells isolated from nGD mice brain
scRNA seq analysis on immune cells isolated from nGD mice brain
PRJNA857039 | ENA
GenomicsRNA seq analysis on immune cells isolated from nGD mice brain
RNA seq analysis on immune cells isolated from nGD mice brain
PRJNA857034 | ENA
TranscriptomicsscRNA seq analysis on immune cells isolated from nGD mice brain
We observed significant changes in gene expression between Wt and nGD brain. nGD brains are highly enriched for immune infiltrates, both microglia and immune infiltrates are activated in nGD brains. Through scRNA seq we identified that, microglia specific Gba deletion lead to higher activation and e...
ORGANISM(S): Mus musculus 
2022-07-13 | GSE207766 | GEO
TranscriptomicsRNA seq analysis on immune cells isolated from nGD mice brain
We observed significant changes in gene expression between Wt and nGD brain. nGD brains are highly enriched for immune infiltrates, both microglia and immune infiltrates are activated in nGD brains. Through scRNA seq we identified that, microglia specific Gba deletion lead to higher activation and e...
ORGANISM(S): Mus musculus 
2022-07-13 | GSE207765 | GEO
UnknownMetabolism and biochemical properties of nicotinamide adenine dinucleotide (NAD) analogs, nicotinamide guanine dinucleotide (NGD) and nicotinamide hypoxanthine dinucleotide (NHD).
Not available
S-EPMC6739475 | biostudies-literature
ProteomicsProteomics analysis of the brain from a Gaucher disease mouse identifies pathological pathways including a possible role for transglutaminase 1
Gaucher disease (GD) is caused by the defective activity of acid beta-glucosidase (GCase) which results from mutations in GBA1. Neurological forms of GD (nGD) can be generated in mice by intra-peritoneal injection of conduritol B-epoxide (CBE) which irreversibly inhibits GCase. Using this approach, ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-12 | MSV000092415 | MassIVE
ProteomicsDistinct ribosome states trigger diverse mRNA quality control pathways
Key protein adapters couple translation to mRNA decay on specific classes of problematic mRNAs in eukaryotes. Slow decoding on nonoptimal codons leads to codon-optimality-mediated decay (COMD) and prolonged arrest at stall sites leads to no-go decay (NGD). The identities of the decay factors underly...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-08-08 | PXD030076 | Pride
Comd Ngd Syh1 Rna decay Smy2 Codon-optimality-mediated decay No-go decay 
UnknownEvaluation of a fully automated bioinformatics tool to predict antibiotic resistance from MRSA genomes.
Not available
S-EPMC7177496 | biostudies-literature
UnknownOverexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance.
Not available
S-EPMC6052485 | biostudies-literature
GenomicsRNA and scRNA seq analyses on immune cells isolated from nGD mice brain
RNA and scRNA seq analyses on immune cells isolated from nGD mice brain
PRJNA857038 | ENA
Sort   by:  
 Page size