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MetabolomicsSoftware tool for internal standard based normalization of lipids, and effect of data-processing strategies on resulting values

BACKGROUND: Lipidomics, the comprehensive measurement of lipids within a biological system or substrate, is an emerging field with significant potential for improving clinical diagnosis and our understanding of health and disease. While lipids diverse biological roles contribute ...

2022-05-17 | MTBLS710 | MetaboLights
TranscriptomicsInnervated and 2 month Denervated Rat EDL muscles
The right legs of 8 Brown-Norway male rats were denervated by a high sciatic nerve section in the hip region of the hind limb.Two months after denervation (6 months of age), extensor digitorum longus (EDL) muscles were removed from the operated legs. The EDL muscles from 8 age-matched non-operated r...
ORGANISM(S): Rattus norvegicus 
2004-09-10 | E-GEOD-1741 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of brown adipose tissue gene expression of IL15-depleted mice under normal diet or diet enriched with the beta3-adrenergic agonist CL 316243
Chronic inflammation is one of the major players in the obesity related metabolic syndrome. However the various inflammatory mediators appear to promote insulin resistance directly or indirectly through their ability to induce the inflammatory cascade. Interleukin-15 (IL-15) is a pro-inflammatory cy...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-55057 | biostudies-arrayexpress
UnknownDifferences In Nursing Home Staff COVID-19 Testing Rates And Odds Of Vaccination Across Work Shifts.
Not available
S-EPMC9990769 | biostudies-literature
UnknownCOVID-19 Mortality Rates Among Nursing Home Residents Declined From March To November 2020.
Not available
S-EPMC8045482 | biostudies-literature
TranscriptomicsRNA-seq from heart tissue of 192 heterogeneous stock rats
We measured heart gene expression in 192 heterogeneous stock rats. These animals were part of a larger cohort that were extensively phenotyped and genotyped and originally published in PMID: 23708188, although the gene expression data here were not included in that study.
ORGANISM(S): Rattus norvegicus 
2023-04-03 | E-MTAB-12701 | biostudies-arrayexpress
TranscriptomicsRNA-seq from amygdala tissue of 205 heterogeneous stock rats
We measured amygdala gene expression in 205 Heterogeneous Stock (N:HS) rats. These animals were part of a larger cohort that were extensively phenotyped and genotyped and originally published in PMID: 23708188, although the gene expression data here were not included in that study.
ORGANISM(S): Rattus norvegicus 
2023-04-03 | E-MTAB-12693 | biostudies-arrayexpress
TranscriptomicsNon-genotoxic Hepatocarcinogens
There is no accurate and well-validated short-term test for non-genotoxic carcinogens, necessitating an expensive two year rodent bioassay before a risk assessment can begin. We have developed a short-term in vivo rat assay that predicts whether non-genotoxic chemicals are likely to induce hepatic t...
ORGANISM(S): Rattus norvegicus 
2007-06-22 | E-GEOD-8251 | biostudies-arrayexpress
ProteomicsMudPIT analyses of the proteins co-purified with FLAG-HA Non-Stop FLAG-IPed from Drosophila melanogaster S2 cells
Protein Complexes Purification- Drosophila S2 cells were stably-transfected with pRmHa3-based inducible expression vectors to produce epitope-tagged Non-stop-2xFLAG-2xHA (Non-stop-FH). Cells stably transfected with empty vector served as negative control. Protein complexes containing Non-stop were p...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2018-07-17 | MSV000082625 | MassIVE
UnknownGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Not available
S-EPMC3944098 | biostudies-literature
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