Brown adipose tissue

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Unknown (2644)
Transcriptomics (908)
Genomics (858)
Proteomics (131)
Metabolomics (40)
Other (10)
Methylation profiling (6)
Models (1)

Organisms

Mus musculus (717)
Rattus norvegicus (179)
Homo sapiens (110)
Ovis aries (10)
Rousettus aegyptiacus (4)
Drosophila melanogaster (3)
Sus scrofa (3)
Ursus arctos (2)
Urocitellus parryii (2)
JC polyomavirus (2)
Betapolyomavirus macacae (2)
human gammaherpesvirus 4 (2)
Betapolyomavirus hominis (2)
Human alphaherpesvirus 1 (2)
Human gammaherpesvirus 8 (2)
Murid gammaherpesvirus 4 (2)
Murid betaherpesvirus 1 (2)
Human immunodeficiency virus 1 (2)
Human betaherpesvirus 5 (2)
Mus (2)
Rhinolophus ferrumequinum (1)
Arvicanthis niloticus (1)
Miniopterus schreibersii (1)
Myotis davidii (1)
Pteropus alecto (1)
Desmodus rotundus (1)
Nothobranchius furzeri (1)
Equus caballus (1)
mixed sample (1)
Callospermophilus lateralis (1)

Organisms

Mus musculus (543)
Homo sapiens (42)
Rattus norvegicus (12)
Ovis aries (6)
Mus (3)
Urocitellus parryii (2)
Lasiopodomys brandtii (1)
Ictidomys tridecemlineatus (1)
Peromyscus maniculatus (1)
Mustela putorius furo (1)
Mesocricetus auratus (1)
unidentified (1)
Mus musculus domesticus (1)
Oryctolagus cuniculus (1)
mouse gut metagenome (1)
gut metagenome (1)

Repository

ENA (756)
geo (551)
biostudies-arrayexpress (457)
pride (89)
MetaboLights (34)
MassIVE (16)
iProX (14)
ExpressionAtlas (13)
jPOST (7)
MetabolomicsWorkbench (5)
EGA (4)
PAXDB (4)
BioModels (1)
GNPS (1)
GPMDB (1)
PanoramaPublic (1)

Tissue

Brown adipose tissue (54)
Liver (20)
White adipose tissue (14)
Heart (11)
Skeletal muscle (8)
Spleen (7)
Lung (5)
Pancreas (4)
Inguinal fat pad (2)
Cerebellum (2)
Diaphragm (2)
Duodenum (2)
Cerebral cortex (2)
White adipose tissue around intestine (1)
White adipose tissue around gonad (1)
Hypothalamus and thalamus (1)
Gastrocnemius (1)
Saliva-secreting gland (1)
Eye (1)
Embryonic tissue (1)
Olfactory bulb (1)
Thymus (1)
Corpus callosum (1)
Brainstem (1)
Visceral abdominal adipose tissue (1)
Colon (1)
Medulla oblongata (1)
Midbrain (1)
Stomach (1)
Cortex of kidney (1)

Disease

Normal (6)
Obesity (5)
Type 2 diabetes mellitus (4)
Disease free (2)
Type 1 diabetes mellitus (2)
Pre-tumoral lesion in a mouse model of human adamantinomatous craniopharyngioma (ACP) (1)
Insulin resistance (1)
None (1)
Not Available (1)
Diabetes (1)
Abdominal aortic aneurysm (1)
Cardiovascular system disease (1)
Diabetes mellitus (1)
Inflammation (1)
Metabolic dysfunction-associated steatotic liver disease (1)
Overweight (1)
Severe acute respiratory syndrome (1)

Technology Type

Mass Spectrometry (94)
Shotgun proteomics (40)
Bottom-up proteomics (23)
Mass spectrometry (21)
Data-dependent acquisition (16)
Mass spectrometry assay (11)
Data-independent acquisition (8)
SWATH MS (5)
Top-down proteomics (5)
ESI (4)
Affinity purification coupled with mass spectrometry proteomics (4)
Gel-based experiment (4)
NMR spectroscopy (2)
SRM/MRM (2)
Other (1)

Instrument Platform

Illumina NovaSeq 6000 (21)
Illumina HiSeq 2500 (16)
NextSeq 500 (15)
Illumina HiSeq 4000 (5)
NextSeq 550 (4)
Orbitrap Fusion Lumos (4)
Q Exactive (4)
Illumina NovaSeq X (3)
Illumina HiSeq 2000 (3)
Illumina HiSeq 3000 (3)
Feature Extraction Version: 7.0,10.5 (2)
The Agilent scanner G2565BA (2)
Agilent�s Microarray Hybridization Oven (2)
NanoDrop ND-1000 Spectrophotometer (NanoDrop Technologies) (2)
Q Exactive HF (2)
Q Exactive HF-X (2)
Axon Instruments GenePix 4000B scanner (1)
Agilent Technologies SureScan Microarray Scanne (1)
Not applicable (1)
428 [Affymetrix] (1)
GeneChip Scanner 3000 [Affymetrix] (1)
GenePix 4000B [Axon Instruments] (1)
NextSeq 2000 (1)
DNBSEQ-G400 (1)
DNBSEQ-T7 (1)
ACCRE (1)
Instrument (1)
CE-TOFMS (1)
LC-TOFMS (1)
MaXis 3G (1)

Publication Date

2025 (103)
2022 (95)
2026 (92)
2015 (90)
2024 (88)
2023 (84)
2014 (74)
2021 (61)
2020 (60)
2019 (57)
2013 (54)
2018 (53)
2011 (44)
2010 (44)
2012 (39)
2016 (36)
2017 (30)
2009 (25)
2008 (25)
2007 (20)
2006 (5)
2005 (3)
2004 (2)

UNIPROT ID/AC

10090.ENSMUSP00000005406 (3)
10090.ENSMUSP00000032399 (3)
10090.ENSMUSP00000050156 (3)
10090.ENSMUSP00000071496 (3)
10090.ENSMUSP00000071763 (3)
10090.ENSMUSP00000072775 (3)
10090.ENSMUSP00000076447 (3)
10090.ENSMUSP00000076538 (3)
10090.ENSMUSP00000078239 (3)
10090.ENSMUSP00000078339 (3)
10090.ENSMUSP00000078625 (3)
10090.ENSMUSP00000078670 (3)
10090.ENSMUSP00000078877 (3)
10090.ENSMUSP00000079727 (3)
10090.ENSMUSP00000079944 (3)
10090.ENSMUSP00000082867 (3)
10090.ENSMUSP00000087466 (3)
10090.ENSMUSP00000087632 (3)
10090.ENSMUSP00000089336 (3)
10090.ENSMUSP00000089519 (3)
10090.ENSMUSP00000090897 (3)
10090.ENSMUSP00000092002 (3)
10090.ENSMUSP00000092345 (3)
10090.ENSMUSP00000092698 (3)
10090.ENSMUSP00000092843 (3)
10090.ENSMUSP00000093124 (3)
10090.ENSMUSP00000094334 (3)
10090.ENSMUSP00000095287 (3)
10090.ENSMUSP00000095794 (3)
10090.ENSMUSP00000095927 (3)

CHEBI ID

CHEBI:28865 (4)
CHEBI:16525 (4)
CHEBI:36274 (3)
CHEBI:41321 (3)
CHEBI:30794 (3)
CHEBI:15420 (1)
CHEBI:7772 (1)
CHEBI:15384 (1)
CHEBI:3110 (1)
CHEBI:29060 (1)
CHEBI:28261 (1)
CHEBI:15389 (1)
CHEBI:16874 (1)
CHEBI:35420 (1)
CHEBI:7274 (1)
CHEBI:16796 (1)
CHEBI:17687 (1)
CHEBI:17697 (1)
CHEBI:16675 (1)
CHEBI:15639 (1)
CHEBI:27870 (1)
CHEBI:16318 (1)
CHEBI:31997 (1)
CHEBI:28940 (1)
CHEBI:28934 (1)
CHEBI:27647 (1)
CHEBI:16463 (1)
CHEBI:34498 (1)
CHEBI:17405 (1)
CHEBI:28541 (1)

Metabolite Name

Hypoxanthine (6)
4-Hydroxybenzaldehyde (4)
(S)-(-)-Perillyl alcohol (3)
LysoPC(14:0/0:0) (3)
LysoPE(0:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) (3)
3-Methyl-2-oxovaleric acid (3)
Lactate (3)
Uracil (3)
Stearidonic acid (3)
Myristoleic acid (3)
5'-Methylthioadenosine (3)
4-Pyridoxic acid (3)
5-Hydroxyindoleacetic acid (3)
GMP (3)
1-Methylhistidine (3)
Decanoylcarnitine (3)
Palmitoylcarnitine (3)
Choline (3)
Taurine (3)
DTMP (3)
Taurocholic acid (3)
Deoxycholic acid (3)
Cholic acid (3)
Niacinamide (3)
Pantothenic acid (3)
Citric acid (3)
Oleamide (3)
Pregnenolone (3)
Guanine (3)
Dodecanoylcarnitine (3)

IsPrivate

False (1)

Model Flag

Non Kinetic (1)

First Public Date

2025 (94)
2024 (89)
2022 (84)
2026 (82)
2023 (81)
2014 (62)
2021 (50)
2020 (50)
2019 (50)
2018 (50)
2017 (24)
2015 (24)
2016 (11)
2013 (5)

Modification

4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (314)
RNA-seq of coding RNA (65)
ChIP-seq (17)
Animal - High-throughput sequencing (12)
RNA-seq of coding RNA from single cells (6)
RNA-seq of non coding RNA (6)
RNA-seq of total RNA (5)
Unknown experiment type (4)
MicroRNA profiling by high throughput sequencing (4)
Methylation profiling by array (4)
Single nucleus RNA sequencing (3)
Animal - Single-cell sequencing (2)
High-throughput sequencing (2)
Spatial transcriptomics by high-throughput sequencing (2)
Other (2)
Methylation profiling by high throughput sequencing (2)
Differential (1)
Human - Single-cell sequencing (1)
Cell line - One-color microarray (1)
Cell line - High-throughput sequencing (1)
Genotyping by array (1)
Comparative genomic hybridization by array (1)
MicroRNA profiling by array (1)

Release Date

2022 (300)
2021 (277)
2020 (254)
2019 (242)
2023 (237)
2025 (228)
2024 (206)
2018 (199)
2017 (190)
2015 (172)
2016 (151)
2014 (140)
2013 (107)
2012 (97)
2011 (71)
2010 (61)
2026 (45)
2009 (38)
2008 (38)
2007 (27)
2006 (8)
2005 (4)
1998 (3)
2004 (2)
2002 (1)
2001 (1)
1999 (1)

Lab affiliation

Cornell University (2)
Howard Hughes Medical Institute Beth Israel Deaconess Medical Center Harvard Medical School (2)
the First Affiliated Hospital of Southern University of Science and Technology (2)
1 Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA 2 Department of Cell Biology, Harvard Medical School, Boston, MA, USA (1)
1 Department of Cancer Biology, Dana–Farber Cancer Institute, Boston, MA, USA. 2 Department of Cell Biology, Harvard Medical School, Boston, MA, USA. (1)
1 Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA 2 Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA 3 Morgridge Institute for Research, Madison, WI, USA 4 National Center for Quantitative Biology of Complex Systems, Madison, WI, USA (1)
1) Department of Cancer Biology, Dana–Farber Cancer Institute, Boston, MA, USA. 2) Department of Cell Biology, Harvard Medical School, Boston, MA, USA. (1)
1.UCSF Diabetes Center, CA, 94143, USA 2.Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, CA, 94143, USA 3.Department of Cell and Tissue Biology, University of California, San Francisco, CA94143, USA (1)
1Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Barcelona, Spain (1)
1Department of Biochemistry, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106 (1)
1Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada 2Department of Biochemistry, McGill University, Montreal, QC, H3G 1Y6, Canada (1)
1Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Singapore 2 Lee Kong Chian School of Medicine, Nanyang Technological University (NTU), Singapore 3 Cardiovascular and Metabolic Disorders Program, Duke-NUS Medical School, Singapore 4Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 5 Department of Endocrinology, Tan Tock Seng Hospital (TTSH), Singapore (1)
Associate Professor Department of Cell and Developmental Biology University of Pennsylvania Perelman School of Medicine (1)
Boston University School of Medicine (1)
Brandenburg University of Technology Cottbus-Senftenberg (1)
Bruce M. Spiegelman, Ph D. Stanley J. Korsmeyer Professor of Cell Biology and Medicine Dana-Farber Cancer Institute, Harvard Medical School bruce_spiegelman@dfci.harvard.edu 617-632-3567 (1)
CNIC (1)
Cell Biology and Physiology, Washington University in St. Louis (1)
Cellular and Molecular Pharmacology, Quantitative Biosciences Institute, Gladstone Institutes, University of California San Francisco, CA, USA (1)
Cellular and Molecular Pharmacology, UCSF (1)
Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, 28029, Spain (1)
Chair of Proteomics and Bioanalytics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany (1)
Chair of Proteomics and Bioanalytics, Technical University of Munich, Freising, Germany (1)
Charles Perkins Centre, School of Medical Sciences, University of Sydney, Sydney, Australia. (1)
Charles Perkins Centre, The University of Sydney (1)
Dana Farber Assistant Professor (1)
Dana Farber Cancer Institute, Dept. Cancer Biology; Harvard Medical Schoool, Dept. Cell Biology (1)
Dana-Farber Cancer Institute, Department of Cancer Biology. Harvard Medical School, Department of Cell Biology. (1)
Dana-Farber Cancer Institute, Dept. Cancer Biology; Harvard Medical School, Dept. Cell Biology (1)
Dep. of Biology, University of Fribourg, Chemin du Musee 10, CH-1700 Fribourg (1)

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Absence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis

Obesity poses a global health challenge, demanding a deeper understanding of adipose tissue (AT) and its mitochondria. This study describes the role of the mitochondrial protein Methylation-controlled J protein (MCJ/DnaJC15) in orchestrating brown adipose tissue (BAT) thermogenesis. Here we show how...

2024-10-31 | MTBLS11505 | MetaboLights

Mouse Brown Adipose Tissue Lipidomics under Cold and Dietary Fat Interventions

This study investigates lipidomic remodeling in mouse brown adipose tissue under a 2 × 3 experimental design involving environmental condition and dietary fatty acid composition. Mice were maintained at room temperature with ad libitum feeding or exposed to 4°C cold conditions with 70% calorie restr...

2026-06-01 | MTBLS14642 | MetaboLights

Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis

Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...

2022-03-03 | MTBLS2436 | MetaboLights

Brown vs White adipose tissue

Not available

ORGANISM(S): Mus musculus

ST000562 | MetabolomicsWorkbench

Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue.

OBJECTIVE: Brown adipose tissue (BAT) burns fatty acids (FAs) to produce heat, and shows diurnal oscillation in glucose and triglyceride (TG)-derived FA-uptake, peaking around wakening. Here we aimed to gain insight in the diurnal regulation of metabolic BAT activity.

2023-11-15 | MTBLS4082 | MetaboLights

A metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS380 | MetaboLights

A metabolomic study of adipose tissue in mice with a disruption of the circadian system

2017-10-27 | MTBLS390 | MetaboLights

A metabolomic study of adipose tissue in mice with a disruption of the circadian system

2017-10-27 | MTBLS382 | MetaboLights

Metabolomics marker of brown adipose tissue in men

Not available

ORGANISM(S): Homo sapiens

ST000550 | MetabolomicsWorkbench

Metabolomics of brown adipose tissue in murine heart failure model

Not available

ORGANISM(S): Mus musculus