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TranscriptomicsMembers of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans
The plasticity of ageing suggests that longevity may be controlled epigenetically by specific alterations in chromatin state. The link between chromatin and ageing has mostly focused on histone deacetylation by the Sir2 family1, 2, but less is known about the role of other histone modifications in l...
ORGANISM(S): Caenorhabditis elegans 
2011-07-08 | E-GEOD-30505 | biostudies-arrayexpress
GenomicsFOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis
FOXO transcription factors are central regulators of longevity from worms to humans. FOXO3 – the FOXO isoform associated with exceptional human longevity – preserves adult neural stem cell pools. Here we identify FOXO3 direct targets genome-wide in primary cultures of adult neural progenitor cells (...
ORGANISM(S): Mus musculus 
2013-08-13 | E-GEOD-48336 | biostudies-arrayexpress
UnknownMemory reconsolidation impairment using the β-adrenergic receptor blocker propranolol reduces nightmare severity in patients with posttraumatic stress disorder: a preliminary study.
Not available
S-EPMC9243278 | biostudies-literature
GenomicsCaenorhabditis elegans
Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans
PRJNA143319 | ENA
GenomicsCaenorhabditis elegans
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans
PRJNA144879 | ENA
TranscriptomicsPax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers [X_laevis_2]
Neural crest development is orchestrated by a complex and still poorly understood gene regulatory network. Premigratory neural crest is induced at the lateral border of the neural plate by the combined action of signaling molecules and transcription factors such as AP2, Gbx2, Pax3 and Zic1. Among th...
ORGANISM(S): Xenopus laevis 
2013-12-28 | E-GEOD-53677 | biostudies-arrayexpress
UnknownAMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs.
Not available
S-EPMC5881568 | biostudies-literature
TranscriptomicsPax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers [Xenopus_laevis]
Neural crest development is orchestrated by a complex and still poorly understood gene regulatory network. Premigratory neural crest is induced at the lateral border of the neural plate by the combined action of signaling molecules and transcription factors such as AP2, Gbx2, Pax3 and Zic1. Among th...
ORGANISM(S): Xenopus laevis 
2013-12-28 | E-GEOD-53678 | biostudies-arrayexpress
TranscriptomicsTransgenerational epigenetic inheritance of longevity in Caenorhabditis elegans
Chromatin modifiers regulate lifespan in several organisms, raising the question of whether changes in chromatin states in the parental generation could be incompletely reprogrammed in the next generation and thereby affect the lifespan of descendents. The histone H3 lysine 4 trimethylation (H3K4me3...
ORGANISM(S): Caenorhabditis elegans 
2011-10-18 | E-GEOD-31043 | biostudies-arrayexpress
TranscriptomicsPax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Xenopus laevis 
2013-12-28 | E-GEOD-53679 | biostudies-arrayexpress
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