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ProteomicsHuman oral cancer brush biopsy iTRAQ
iTRAQ-based comparison of proteins derived from oral cells collected by brush biopsy. Protein abundance levels compared between oral pre-malignant cells, oral cancer cells and healthy normal cells, all collected from human patients. Two separate iTRAQ labeled biological replicate analyses were con...
ORGANISM(S): Homo sapiens (Human) 
2014-05-07 | PXD000807 | Pride
Human Oral cancer Brush biopsy Itraq 
ProteomicsHuman oral cancer brush biopsy iTRAQ
iTRAQ-based comparison of proteins derived from oral cells collected by brush biopsy. Protein abundance levels compared between oral pre-malignant cells, oral cancer cells and healthy normal cells, all collected from human patients. Two separate iTRAQ labeled biological replicate analyses were con...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079994 | MassIVE
GenomicsOral premalignant lesions (OPLs) with genomic alterations have a heightened risk of evolving into oral squamous cell carcinoma (OSCC). Currently, genomic data are obtained through invasive tissue biopsy. Brush biopsy has been utilized for diagnosing dysplasia but its effectiveness in reflecting the complete genomic landscape of OPLs remains uncertain. This study investigates the potential of brush biopsy samples in accurately reconstructing the genomic profile of OPLs. We analyzed single nucleotide variants (SNVs), copy number aberrations (CNAs), and subclonal structures in paired tissue and brush biopsy samples from a patient with both OPL and OSCC lesions. The results showed that brush biopsy can effectively reflect about 90% of SNVs and similar CNA profiles as those found in tissue biopsies. It was specific, as normal oral epithelium didn’t share these genomic alterations. Interestingly, brush biopsy revealed shared SNVs and CNAs between the distinct OPL and OSCC lesions, indicating...
Reconstructing oral cavity tumor evolution through brush biopsy
PRJEB71314 | ENA
UnknownReconstructing oral cavity tumor evolution through brush biopsy.
Not available
S-EPMC11439926 | biostudies-literature
TranscriptomicsGene expression changes associated with the airway wall response to injury
Understanding the way in which the airway heals in response to injury is fundamental to dissecting the mechanisms underlying airway disease pathology. Only limited data is available in relation to in vivo characterisation of the molecular features of repair in the airway. This study sought to charac...
ORGANISM(S): Ovis aries 
2013-05-27 | E-GEOD-37086 | biostudies-arrayexpress
UnknownmicroRNA from brush biopsy to characterize oral squamous cell carcinoma epithelium.
Not available
S-EPMC5275769 | biostudies-literature
UnknownComparison of brush and biopsy sampling methods of the ileal pouch for assessment of mucosa-associated microbiota of human subjects.
Not available
S-EPMC3931571 | biostudies-literature
GenomicsStrong correlation between air-liquid interface cultures and in vivo transcriptomics of nasal brush biopsy
Strong correlation between air-liquid interface cultures and in vivo transcriptomics of nasal brush biopsy
PRJNA606035 | ENA
TranscriptomicsHuman intranasal olfactory biopsy analysis of Alzheimer's Disease subjects
Single-cell RNA sequencing was performed on brush biopsy samples from the human olfactory epithelium (n = 22 donors) spanning control (n = 6), pre-clinical (n = 9) and clinical (n = 7) Alzheimer’s disease stages. The dataset comprises ~200,000 high-quality live cells encompassing neuronal, epithelia...
ORGANISM(S): Homo sapiens 
2026-02-04 | GSE302937 | GEO
UnknownImmunoexpression of oral brush biopsy enhances the accuracy of diagnosis for oral lichen planus and lichenoid lesions.
Not available
S-EPMC9542982 | biostudies-literature
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