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Identifying BTLA interacting proteins in mouse CD4+ effector T cells expressing BTLA at endogenous levels and after stimulation with pervanadate.
ORGANISM(S): Mus musculus (Mouse) 
2019-05-06 | PXD010863 | Pride
Adoptive T-cell Therapy (ACT) involves using tumor-infiltrating lymphocytes (TIL) isolated from metastatic melanoma and expanding them ex vivo prior to infusion into lympho-depleted patients. This is one of the most promising approaches to treat metastatic melanoma, with the rates of clinical respo...
ORGANISM(S): Homo sapiens 
BTLA NTN scRNAseq
Regulation of Intestinal microbiome diversity by BTLA and HVEM
Thymocytes TCR repertoire from regular B6 and Btla KO mice
BTLA and PD-1 signals attenuate TCR-mediated gene expression
Analysis of BTLA regulated transcripts in human B and CD4+ T cells
Tumor cell-intrinsic BTLA receptor inhibits the proliferation of tumor cells via ERK1/2
Goal is to investigate the molecular changes in renal leukocytes during nephrotoxic nephritis in BTLA-KO mice compared to wild-type mice
ORGANISM(S): Mus musculus 
2023-07-22 | GSE223534 | GEO
Deletion of BTLA up regulates CD5 expression. Higher CD5 expression during thymic selection is associated with increased self-recognition, suggesting that BTLA might be needed early to establish self-tolerance. To investigate whether the regulation of CD5 by BTLA is TCR-repertoire independent, we pe...
ORGANISM(S): Mus musculus 
2024-11-06 | GSE269212 | GEO
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