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ProteomicsAblation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation
Butyrophilin 1A1 (BTN1A1) was first identified as a major integral protein of both the apical surface of mammary epithelial cells during lactation and the surface membrane surrounding lipid droplets in milk. Current evidence supports a role for BTN1A1 in the secretion of milk lipids as a membrane re...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-20 | PXD021249 | Pride
Btn1a1 Butyrophilin 1a1 Lactation Milk-lipid secretion 
UnknownBTN1A1 is a novel immune checkpoint mutually exclusive to PD-L1.
Not available
S-EPMC10941171 | biostudies-literature
UnknownAkt1 is essential for postnatal mammary gland development, function, and the expression of Btn1a1.
Not available
S-EPMC3168520 | biostudies-literature
TranscriptomicsComparison of Differences in Mouse Mammary gland gene expression data at POSTNATAL DAY 70 in Akt1wildtype versus Akt1-deficient mice
Akt1, a serine-threonine protein kinase member of the PKB/Akt gene family, plays a critical role in the regulation of several cellular processes including cell proliferation and apoptosis. In this study, we utilized Akt1+/+ and Akt1¬-/- C57/Bl6 female mice to demonstrate that Akt1 is required for n...
ORGANISM(S): Mus musculus 
2011-07-14 | E-GEOD-30671 | biostudies-arrayexpress
UnknownKnockout of butyrophilin subfamily 1 member A1 (BTN1A1) alters lipid droplet formation and phospholipid composition in bovine mammary epithelial cells.
Not available
S-EPMC7333294 | biostudies-literature
GenomicsThe butyrophilin 1a1 knock-out mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation
The butyrophilin 1a1 knock-out mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation
PRJNA754402 | ENA
TranscriptomicsThe butyrophilin 1a1 knock-out mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation
Purpose: To assess global changes to the levels of mRNA and protein in butyrophilin-null mice (Btn1a1-/-), which were previously shown to be defective in regulated milk-lipid secretion in the lactating mammary gland. Methods: mRNA profiles of wild-type (WT) and Btn1a1-/-mice were generated by mRNA/c...
ORGANISM(S): Mus musculus 
2021-09-20 | GSE182075 | GEO
UnknownThe butyrophilin 1a1 knockout mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation.
Not available
S-EPMC8664049 | biostudies-literature
UnknownOccludin is a target of Src kinase and promotes lipid secretion by binding to BTN1a1 and XOR.
Not available
S-EPMC8797263 | biostudies-literature
UnknownTDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh.
Not available
S-EPMC6969145 | biostudies-literature
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