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ProteomicsHs_TERRA_pull-down_SILAC
SILAC-labeled human nuclear cell lysates in an RNA pull-down experiment
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe005032 | PeptideAtlas
TranscriptomicsGene regulation in hematopoietic cells by Pcgf1 in a Runx1 null background
The transcription factor Runx1 is essential for the establishment of definitive hematopoiesis during embryonic development. In adult blood homeostasis, Runx1 plays a pivotal role in the maturation of lymphocytes and megakaryocytes. Furthermore, Runx1 is required for the regulation of hematopoietic s...
ORGANISM(S): Mus musculus 
2012-06-17 | E-GEOD-33280 | biostudies-arrayexpress
TranscriptomicsInfluence of cell permeable Tre-recombinase (CPTR) treatment on T-cell gene expression
CEM-ss cells were treated with or without a recombinantly expressed recombinase and gene expression profiles were compared. Two-condition experiment, Untreated CEM-ss vs. CPTR treated CEM-ss cells
ORGANISM(S): Homo sapiens 
2012-02-22 | E-GEOD-32643 | biostudies-arrayexpress
TranscriptomicsRNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug.
Acute myeloid leukemia (AML) is characterized by a marked genetic heterogeneity, which complicates the development of novel therapeutics. The delineation of pathways essential within the patient-individual mutational background might overcome this limitation and facilitate personalized treatment. We...
ORGANISM(S): Homo sapiens 
2015-05-16 | E-GEOD-68925 | biostudies-arrayexpress
UnknownCombining T-cell-specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors.
Not available
S-EPMC7686896 | biostudies-literature
TranscriptomicsGenome-scale RNAi profiling of cell division in human tissue culture cells
Cell division is a fundamental process for multicellula organisation. Here we report a genome-scale RNAi screen in HeLa cells designed to identify human genes important for cell division. We utilized a library of endoribonuclease-prepared siRNAs (esiRNAs) for gene-silencing and used DNA content an...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-9176 | biostudies-arrayexpress
ProteomicsA human interactome in three quantitative dimensions organized by stoichiometries and abundances -- auxiliary dataset
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed glob...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Saccharomyces Cerevisiae (ncbitaxon:4932) Mus Musculus (ncbitaxon:10090) 
2016-10-21 | MSV000080271 | MassIVE
ProteomicsA human interactome in three quantitative dimensions organized by stoichiometries and abundances
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed glob...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2016-06-17 | MSV000079835 | MassIVE
UnknownRisk of strong antibody decline in dialysis and transplant patients after SARS-CoV-2mRNA vaccination: Six months data from the observational Dia-Vacc study.
Not available
S-EPMC8995854 | biostudies-literature
UnknownThe drug-induced phenotypic landscape of colorectal cancer organoids.
Not available
S-EPMC9170716 | biostudies-literature
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