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ProteomicsThe Role of Core Virulence Kinase Bud32 in Iron Homeostasis Regulation in Cryptococcus neoformans
The core virulence kinase Bud32, which is critical for lung and brain infections, influences the production of major virulence factors in Cryptococcus neoformans, including capsule formation, melanin production, and growth at 37°C. This study explores the role of Bud32 in regulation of iron homeosta...
ORGANISM(S): Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) 
2025-07-23 | PXD056847 | Pride
Bud32  grx4  cir1  hapx  rim101 
ProteomicsThe Role of Core Virulence Kinase Bud32 in Iron Homeostasis Regulation in Cryptococcus neoformans
The core virulence kinase Bud32, which is critical for lung and brain infections, influences the production of major virulence factors in Cryptococcus neoformans, including capsule formation, melanin production, and growth at 37°C. This study explores the role of Bud32 in regulation of iron homeosta...
ORGANISM(S): Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) 
2025-07-23 | PXD056845 | Pride
Bud32  grx4  cir1  hapx  rim101 
UnknownStructures of KEOPS bound to tRNA reveal functional roles of the kinase Bud32.
Not available
S-EPMC11621456 | biostudies-literature
UnknownCrystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
Not available
S-EPMC4381065 | biostudies-literature
UnknownStructure of the archaeal Kae1/Bud32 fusion protein MJ1130: a model for the eukaryotic EKC/KEOPS subcomplex.
Not available
S-EPMC2529370 | biostudies-literature
TranscriptomicsUnravelling the pathobiological role of the fungal KEOPS complex in Cryptococcus neoformans
The kinase, putative endopeptidase and other peptides of small size (KEOPS) complex plays critical cellular functions in eukaryotes, but its pathobiological roles remains elusive in fungal pathogens. Here we comprehensively analyze the pathobiological functions of the KEOPS complex in fungal meningo...
ORGANISM(S): Cryptococcus neoformans 
2022-10-18 | GSE208333 | GEO
UnknownThe kinase Bud32 regulates iron homeostasis in fungal pathogen Cryptococcus neoformans
Not available
S-EPMC12332752 | biostudies-literature
UnknownAtomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Not available
S-EPMC3098719 | biostudies-literature
UnknownUnraveling the Pathobiological Role of the Fungal KEOPS Complex in Cryptococcus neoformans.
Not available
S-EPMC9765431 | biostudies-literature
UnknownAuthor Correction: Structures of KEOPS bound to tRNA reveal functional roles of the kinase Bud32.
Not available
S-EPMC12289995 | biostudies-literature
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