Sort   by:  
 Page size 
TranscriptomicsDifferent propensity in hematopoietic differentiation potential among distinct human pluripotent stem cell lines
Lineage-specific differentiation potential varies among different human pluripotent stem cell (hPSC) lines. A stem cell bank may advice researchers on which hPSCs exhibit the highest differentiation potential for a certain lineage. In this study, we aimed at characterizing the hematopoietic differen...
ORGANISM(S): Homo sapiens 
2010-07-24 | E-GEOD-23091 | biostudies-arrayexpress
TranscriptomicsFLT3 activation cooperates with MLL-AF4 fusion gene to abrogate the hematopoietic specification of human ESCs
MLL-AF4 is a hallmark genomic aberration which arises prenatally in high-risk infant acute lymphoblastic leukemia (ALL). In human embryonic stem cells (hESCs), MLL-AF4 skewed hemato-endothelial specification but was not sufficient for transformation. Additional cooperating genetic insults seem requi...
ORGANISM(S): Homo sapiens 
2013-06-04 | E-GEOD-40103 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiles of Arabidopsis stomataless mutants
Stomataless Arabidopsis thaliana mutants spch-3 and mute-3 are extreme dwarfs but can produce cotyledons and tiny leaves, providing a system to interrogate plant life in the absence of stomata. To this end, we compared the transcriptomes of mutant cotyledons lacking SPCH or MUTE functions, and there...
ORGANISM(S): Arabidopsis thaliana 
2015-07-02 | E-MTAB-3416 | biostudies-arrayexpress
TranscriptomicsCopy number alterations in pleural mesothelioma
Integrated profiling of somatic molecular alterations present in tumors is necessary to further our understanding of the tumorigenic process. We investigated the potential relationships between gene copy number alterations and DNA methylation profiles in a case series of pleural mesotheliomas (n=23)...
ORGANISM(S): Homo sapiens 
2010-07-31 | E-GEOD-21057 | biostudies-arrayexpress
TranscriptomicsA promoter DNA demethylation landscape of human hematopoietic differentiation
Global mechanisms defining the gene expression programs specific for hematopoiesis are still not fully understood. Here, we show that promoter DNA demethylation is associated the activation of hematopoietic-specific genes. Using genome-wide promoter methylation arrays, we identified 694 hematopoie...
ORGANISM(S): Homo sapiens 
2011-09-14 | E-GEOD-30090 | biostudies-arrayexpress
TranscriptomicsDevelopment of gene expression profile on different sampling sites of the Ebro River
The zebra mussel is present in Spain since early 2000,s, when it was discovered in the lower part of the Ebro river. To study the gene expression pattern of different populations of zebra mussel a long the Ebro River we use a custom microarray developed in our laboratory, using 4057 publicly availab...
ORGANISM(S): Dreissena polymorpha 
2012-10-10 | E-GEOD-41416 | biostudies-arrayexpress
UnknownCorrelation of PD-L1 Expression with Tumor Mutation Burden and Gene Signatures for Prognosis in Early-Stage Squamous Cell Lung Carcinoma.
Not available
S-EPMC6309634 | biostudies-literature
UnknownDeletion at 6q24.2-26 predicts longer survival of high-grade serous epithelial ovarian cancer patients.
Not available
S-EPMC5528660 | biostudies-literature
UnknownStructural determinants of dual incretin receptor agonism by tirzepatide.
Not available
S-EPMC9060465 | biostudies-literature
TranscriptomicsMelanoma-derived exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through upregulation of the MET oncoprotein.
Tumor-derived exosomes are emerging as mediators of tumorigenesis with a tissue-specific address and message. We explored the function of melanoma-derived exosomes in formation of primary tumors and metastatic progression in both murine models and patients. Whereas exosomes from highly metastatic me...
ORGANISM(S): Mus musculus 
2012-05-26 | E-GEOD-36584 | biostudies-arrayexpress
Sort   by:  
 Page size