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TranscriptomicsATAC-seq of mESCs differentiation into neurons
Mouse WT129 ESCs were differentiated into glutamatergic neurons and samples were collected at days 0 (mESCs), 4 (embryoid bodies), 8 (neuronal precursors) and 12 (neurons). ATAC-seq experiment in 4 biological replicates was performed at 4 indicated above time points to profile chromatin structure ch...
ORGANISM(S): Mus musculus 
2020-05-20 | E-MTAB-8194 | biostudies-arrayexpress
GenomicsSox2 ChIP-seq in mESCs and neurons
Mouse WT129 ESCs and differentiated from them within 12 days glutamatergic neurons were used for the ChiP-seq experiment with an antibody against Sox2 protein. ES stands for mESCs, NP for neurons, inputs are provided for both cell types.
ORGANISM(S): Mus musculus 
2020-05-21 | E-MTAB-8196 | biostudies-arrayexpress
TranscriptomicsRNA-seq of cortical synaptoneurosomes from MNK1 and MNK2 KO mice.
The experiment was designed to study which genes are differentially expressed on mRNA level in MNK1 or MNK2 KO mice, focusing on synaptic compartment, and further correlate these genes with mis-expressed proteins in the same genotype mice. This would reveal whether MNK1 or MNK2 KOs mostly affect tra...
ORGANISM(S): Mus musculus 
2026-02-10 | E-MTAB-16276 | biostudies-arrayexpress
TranscriptomicsRNA-seq of in vitro reprogrammed mouse pericytes to oligodendrocytes
Direct conversion of pericytes (PCs) or mouse embryonic fibroblasts (MEFs) into induced oligodendrocytes (iOPCs) by ectopic expression of Olig2, Sox10 and Nkx6.2 was assessed by transcriptome profiling (RNA-seq). Samples were collected before and after direct conversion (for PCs at 3 different time ...
ORGANISM(S): Mus musculus 
2021-03-07 | E-MTAB-8453 | biostudies-arrayexpress
TranscriptomicsATAC-seq of in vitro reprogrammed mouse pericytes to oligodendrocytes
Direct conversion of pericytes (PCs) into induced oligodendrocytes (iOPCs) by ectopic expression of Olig2 and Sox10 (2F) was assessed by chromatin accessibility profiling (by ATAC-seq). Samples were collected before and after direct conversion (at 3 different time points/passages - p5, p15 and p25).
ORGANISM(S): Mus musculus 
2021-03-07 | E-MTAB-8452 | biostudies-arrayexpress
TranscriptomicsRNA-seq in differentiation of WT129 mESCs to neurons
Mouse WT129 ESCs were differentiated into glutamatergic neurons and samples were collected at days 0 (mESCs), 4 (embryoid bodies), 8 (neuronal precursors) and 12 (neurons). These are RNA-seq data to profile RNA expression during differentiation.
ORGANISM(S): Mus musculus 
2020-05-21 | E-MTAB-8197 | biostudies-arrayexpress
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