Sort   by:  
 Page size 
TranscriptomicsGlycemic index differences of high-fat diets modulate primarily lipid metabolism in murine adipose tissue
We previously reported that a low versus high glycemic index (GI) diet on a high fat (30% kcal fat) background (LGI and HGI, respectively) significantly retarded adverse health effects in C57BL/6J male mice. The LGI diet enhanced whole body insulin sensitivity and repressed high fat diet-induced bod...
ORGANISM(S): Mus musculus 
2011-09-12 | E-GEOD-26930 | biostudies-arrayexpress
TranscriptomicsMuscle Involvement in Preservation of Metabolic Flexibility by a Combination Treatment using n-3 PUFA and Rosiglitazone in Dietary-Obese Mice
Impaired resistance to insulin, the key defect in type 2 diabetes (T2D), is associated with a low capacity to adapt fuel oxidation to fuel availability, i.e., metabolic inflexibility. The hampered metabolic adaptability triggers a further damage of insulin signaling. Since skeletal muscle is the mai...
ORGANISM(S): Mus musculus 
2012-09-07 | E-GEOD-36717 | biostudies-arrayexpress
TranscriptomicsA high fat diet causes obesity and insulin resistance in mice, but induces small changes in the muscle transcriptome
An 8-week high fat palm oil diet causes obesity and insulin resistance in C57BL/6J mice, but induces only small changes in the muscle transcriptome. Introduction: The metabolic syndrome (MS) is a cluster of metabolic abnormalities linked to an increased risk of type 2 diabetes and cardiovascular dis...
ORGANISM(S): Mus musculus 
2010-08-10 | E-GEOD-17576 | biostudies-arrayexpress
TranscriptomicsMuscle Involvement in Preservation of Metabolic Flexibility by Treatment using n-3 PUFA or Rosiglitazone in Dietary-Obese Mice
Impaired resistance to insulin, the key defect in type 2 diabetes (T2D), is associated with a low capacity to adapt fuel oxidation to fuel availability, i.e., metabolic inflexibility. The hampered metabolic adaptability triggers a further damage of insulin signaling. Since skeletal muscle is the mai...
ORGANISM(S): Mus musculus 
2012-09-07 | E-GEOD-36716 | biostudies-arrayexpress
TranscriptomicsQuercetin induces hepatic lipid omega-oxidation and lowers serum lipid levels in mice
Elevated circulating lipid levels are known risk factors for cardiovascular diseases (CVD). In order to examine the effects of quercetin on hepatic lipid metabolism and detailed serum lipid profiles, mice received a mild-high-fat diet without (control) or with supplementation of 0.33% (w/w) querceti...
ORGANISM(S): Mus musculus 
2013-02-05 | E-GEOD-39140 | biostudies-arrayexpress
TranscriptomicsMuscle Involvement in Preservation of Metabolic Flexibility by Treatment using n-3 PUFA, Rosiglitazone, and a combination of both
This SuperSeries is composed of the following subset Series: GSE36716: Muscle Involvement in Preservation of Metabolic Flexibility by Treatment using n-3 PUFA or Rosiglitazone in Dietary-Obese Mice GSE36717: Muscle Involvement in Preservation of Metabolic Flexibility by a Combination Treatment using...
ORGANISM(S): Mus musculus 
2012-09-07 | E-GEOD-36718 | biostudies-arrayexpress
UnknownChemically Enhanced Immunogenicity of Bacteria by Supramolecular Functionalization with an Adjuvant.
Not available
S-EPMC10098600 | biostudies-literature
TranscriptomicsTranscription profiling of mouse small intestine following a four week diet high high in polyunsaturated fatty acids of marine origin
Dietary polyunsaturated fatty acids (PUFA) act as potent natural hypolipidemics and are linked to many health benefits in humans and in animal models. Mice fed long-term a high fat diet, in which medium-chain alpha linoleic acid (ALA) was partially replaced by long-chain docosahexaenoic (DHA) and ei...
ORGANISM(S): Mus musculus 
2009-04-16 | E-GEOD-11936 | biostudies-arrayexpress
UnknownRecombinant long-acting glycoPEGylated factor IX in hemophilia B: a multinational randomized phase 3 trial.
Not available
S-EPMC4271178 | biostudies-literature
UnknownA model of healthy aging based on smartphone interactions reveals advanced behavioral age in neurological disease.
Not available
S-EPMC9418593 | biostudies-literature
Sort   by:  
 Page size