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ProteomicsEccrine sweat proteomics for the diagnosis of cystic fibrosis
In clinical routine, the diagnosis of cystic fibrosis (CF) is still a challenge due to the limitations of diagnosis guidelines and tests. A diagnosis test of choice, the sweat test measures eccrine sweat chloride concentration as a byproduct of the eccrine sweat gland CFTR function. Despite the comb...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD028518 | Pride
Human Orbitrap Biomarkers Eccrine sweat Cystic fibrosis Shotgun proteomics 
ProteomicsiTRAQ LLC-PK1 CnI - Sum of peak intensities outperforms peak area integration in iTRAQ protein expression measurement by LC-MS/MS using a TripleTOF 5600+ platform
In the field of quantitative proteomics, the Isobaric Tags for Relative & Absolute Quanti-tation (iTRAQ) technology has demonstrated efficacy for proteome monitoring despite its lack of a consensus for data handling. In this study, after peptide and protein identification, we com-pared the widesprea...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2019-08-19 | PXD007891 | Pride
Llc pk-1 Itraq Calcineurin inhibitors 
ProteomicsHuman eccrine sweat shotgun proteomics for personalized monitoring and therapy
The potential of eccrine sweat as a bio-fluid of interest for diagnosis and personalized therapy has not yet been fully evaluated, due to the lack of in-depth sweat characterization studies. Thanks to recent developments in the field of omics together with the availability of accredited eccrine swea...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD025899 | Pride
Human Eccrine sweat Lc-ms/ms Shotgun proteomics 
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