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Transcriptomicsset2 buratowski lab
H3K36 methylation by Set2 targets Rpd3S histone deacetylase to 3’ transcribed regions, repressing internal cryptic promoters and slowing elongation. To further explore the function of this pathway, global transcription was analyzed in yeast experiencing a series of carbon source shifts. Many pr...
ORGANISM(S): Saccharomyces cerevisiae 
2016-09-25 | E-MTAB-4268 | biostudies-arrayexpress
TranscriptomicsRatios for unsync cells
Chromatin plays roles in processes governed by different time scales. To assay the dynamic behaviour of chromatin in living cells, we used genomic tiling arrays to measure histone H3 turnover in G1-arrested S. cerevisiae at single-nucleosome resolution over 4% of the genome, and over the entire geno...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-11 | E-GEOD-6664 | biostudies-arrayexpress
TranscriptomicsRatios for G1 arrested cells (Printed array)
Chromatin plays roles in processes governed by different time scales. To assay the dynamic behaviour of chromatin in living cells, we used genomic tiling arrays to measure histone H3 turnover in G1-arrested S. cerevisiae at single-nucleosome resolution over 4% of the genome, and over the entire geno...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-11 | E-GEOD-6665 | biostudies-arrayexpress
TranscriptomicsNucleosome occupancy
Chromatin plays roles in processes governed by different time scales. To assay the dynamic behaviour of chromatin in living cells, we used genomic tiling arrays to measure histone H3 turnover in G1-arrested S. cerevisiae at single-nucleosome resolution over 4% of the genome, and over the entire geno...
ORGANISM(S): Saccharomyces cerevisiae 
2007-05-16 | E-GEOD-6668 | biostudies-arrayexpress
TranscriptomicsPolII occupancy
Chromatin plays roles in processes governed by different time scales. To assay the dynamic behaviour of chromatin in living cells, we used genomic tiling arrays to measure histone H3 turnover in G1-arrested S. cerevisiae at single-nucleosome resolution over 4% of the genome, and over the entire geno...
ORGANISM(S): Saccharomyces cerevisiae 
2007-05-16 | E-GEOD-6667 | biostudies-arrayexpress
TranscriptomicsH3 occupancy
Chromatin plays roles in processes governed by different time scales. To assay the dynamic behaviour of chromatin in living cells, we used genomic tiling arrays to measure histone H3 turnover in G1-arrested S. cerevisiae at single-nucleosome resolution over 4% of the genome, and over the entire geno...
ORGANISM(S): Saccharomyces cerevisiae 
2007-05-16 | E-GEOD-6669 | biostudies-arrayexpress
TranscriptomicsRNA Polymerase mapping during stress responses reveals widespread nonproductive transcription in yeast
The use of genome-wide RNA abundance profiling by microarrays and deep sequencing has spurred a revolution in our understanding of transcriptional control. However, changes in mRNA abundance reflect the combined effect of changes in RNA production, processing, and degradation, and thus, mRNA levels ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-16 | E-GEOD-22675 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by tiling array of yeast undergoing a series of carbon source shifts to discern how Set3C affects gene expression
Set3 complex (Set3C) binds histone H3 dimethylated at lysine 4 (H3K4me2) to mediate deacetylation of histones in 5Õ transcribed regions. To discern how Set3C affects gene expression, genome-wide transcription was analyzed in yeast undergoing a series of carbon source shifts. Deleting SET3 primarily ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-09-05 | E-MTAB-1250 | biostudies-arrayexpress
TranscriptomicsGene deletion expression profiles of yeast chromatin modifiers
Packaging of DNA into chromatin has a profound impact on gene expression. To understand how changes in chromatin influence transcription, we analyzed 165 mutants of chromatin machinery components in Saccharomyces cerevisiae. mRNA expression patterns change in 80% of mutants, always with specific eff...
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-23 | E-GEOD-25909 | biostudies-arrayexpress
TranscriptomicsFeedback control of Set1 protein levels is important for proper H3K4 methylation patterns
Methylation of histone H3 lysine 4 by the Set1 subunit of COMPASS correlates withactive transcription. Here we show that Set1 levels are regulated by protein degradation in response to multiple signals. Set1 levels are greatly reduced when COMPASS recruitment to genes, H3K4 methylation, or transcrip...
ORGANISM(S): Saccharomyces cerevisiae 
2014-02-28 | E-GEOD-55082 | biostudies-arrayexpress
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