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UnknownDiterpenoid Alkaloids and One Lignan from the Roots of Aconitum pendulum Busch.
Not available
S-EPMC6872700 | biostudies-literature
TranscriptomicsCX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (RNA-seq)
Memory T cells are important for protective immunity against infectious microorganisms. Such protection is achieved by cooperative action of memory T cell populations that differ in their tissue localization and functionality. We report on the identification of the fractalkine receptor CX3CR1 as mar...
ORGANISM(S): Homo sapiens 
2016-06-10 | E-GEOD-63144 | biostudies-arrayexpress
TranscriptomicsCX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (expression)
Memory T cells are important for protective immunity against infectious microorganisms. Such protection is achieved by cooperative action of memory T cell populations that differ in their tissue localization and functionality. We report on the identification of the fractalkine receptor CX3CR1 as mar...
ORGANISM(S): Mus musculus 
2016-06-10 | E-GEOD-63118 | biostudies-arrayexpress
TranscriptomicsIntrathymic origins of T-ALL
Leukemia cells are considered developmentally 'frozen', and their phenotype is thought to reflect their stage of origin. To gain insights into the cell population from which T-ALL arises, we compared by global gene expression profiling T-ALL samples (n = 10) to different stages of T cell development...
ORGANISM(S): Mus musculus 
2014-05-16 | E-GEOD-56416 | biostudies-arrayexpress
GenomicsTargeted T cell receptor gene editing provides predictable T cell product function for immunotherapy
Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy
PRJNA744203 | ENA
ProteomicsImpact of de novo variants in the PSMC5 coding the AAA-ATPase proteasome subunit PSMC5/Rpt6 on the protein pattern of patient-derived primary T-cells in comparison to their wild-type counterparts.
To better understand the cellular consequences of mutations in the AAA-ATPase proteasome subunit PSMC5/Rpt6, we performed a mass spectrometry-based comparative analysis of the T-cell proteome of subjects with PSMC5 mutations to that of their wild-type counterparts.
ORGANISM(S): Homo sapiens (Human) 
2025-08-07 | PXD048558 | Pride
Protein homeostasis Psmc5 variants Proteasome Primary t-cells 
Transcriptomicsregulatory T cells in human pregnancy
Transplacental immune programming refers to the concept that during pregnancy, significant crosstalk occurs between the maternal and fetal immune system, with consequent long‐term effects especially for the offspring. In this study, we searched for evidence of transplacental programming in cellul...
ORGANISM(S): Homo sapiens 
2013-11-04 | E-GEOD-31976 | biostudies-arrayexpress
TranscriptomicsExpression data from Human CD40L+ Tcells
To assess the nature of CD8+CD40L+ memory Tcells, we compared the gene expression to CD8+CD40L- and CD4+ counterparts, and found similarities in expression of genes encoding cytokines PBMCs were isolated from five healthy donors. The cells were stimulated with PMA/Ionomycin for 6 h, and subsequently...
ORGANISM(S): Homo sapiens 
2013-08-05 | E-GEOD-44126 | biostudies-arrayexpress
TranscriptomicsAnalysis of mouse T cell transcription profile after co-culture with BaF3 cells with or without the oncogenic point mutation JAK2 V617F
The activation of PD-1 (Programmed Death receptor-1) on T cells can cause T cell exhaustion and immune tolerance. Some tumors up-regulate the expression of the ligand of PD-1, namely PD-L1 (Programmed Death Receptor-Ligand 1), thus preventing anti-tumor immune response and promoting immune-escape. P...
ORGANISM(S): Mus musculus 
2018-12-01 | E-MTAB-5028 | biostudies-arrayexpress
UnknownFLT3-regulated antigens as targets for leukemia-reactive cytotoxic T lymphocytes.
Not available
S-EPMC3255276 | biostudies-literature
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