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TranscriptomicsTiling path analysis of Drosophila Schneider 2 cultured cells to map forum domains
Forum domains are stretches of chromosomal DNA that are excised from eukaryotic chromosomes during their spontaneous non-random fragmentation. Mostly forum domains are of 50-200 kb in length, although larger domains, up to 500 - 700 kb, are also observed.

We performed a genome-wide mapping o...
ORGANISM(S): Drosophila melanogaster 
2010-11-01 | E-MEXP-2468 | biostudies-arrayexpress
TranscriptomicsDeeply conserved gene-regulatory functions of carboxy-terminal domains in dictyostelid C-module-binding factors
We describe the gene expression pattern of a Dictyostelium discoideum mutant depleted in the C-module-binding factor (CbfA) and autonomous gene-regulatory activities of CbfA carboxy-terminal domains (CbfA-CTDs) Comparison of gene expression in growing cells of a CbfA mutant compared to wild-type
ORGANISM(S): Dictyostelium discoideum 
2012-06-03 | E-GEOD-38418 | biostudies-arrayexpress
TranscriptomicsDeeply conserved gene-regulatory functions of carboxy-terminal domains in dictyostelid C-module-binding factors
We describe the gene expression pattern of a Dictyostelium discoideum mutant depleted in the C-module-binding factor (CbfA) and autonomous gene-regulatory activities of CbfA carboxy-terminal domains (CbfA-CTDs)
ORGANISM(S): Dictyostelium discoideum 
2012-06-03 | GSE38418 | GEO
ProteomicsEssential role of the Pax5 C-terminal domain in controlling B cell commitment and development
Pax5 controls B-cell commitment, development and immunity by repressing B-lineage-inappropriate genes and activating B-cell-specific genes. In addition to the N-terminal DNA-binding paired domain, Pax5 contains a conserved octapeptide, partial homeodomain and C-terminal sequences with transactivatin...
ORGANISM(S): Mus musculus (Mouse) 
2023-08-24 | PXD040424 | Pride
Co-repressors C-terminal regulatory domains Gene activation Co-activators Pax5 Gene repression 
ProteomicsThe C-terminal domains SnRK2-box and ABA-box have a role in sugarcane SnRK2s auto-activation and activity
Resistance to drought stress is fundamental to plant survival and development. Abscisic acid (ABA) is one of the major hormones involved in different types of abiotic and biotic stress responses. ABA intracellular signaling has been extensively explored in Arabidopsis thaliana and occurs via a phosp...
ORGANISM(S): Saccharum hybrid cultivar x Sorghum bicolor 
2019-11-13 | PXD014298 | Pride
Snrk2 Abiotic stress Crop plant Abscisic acid Sugarcane Kinase regulation 
UnknownRegulatory interactions between APOBEC3B N- and C-terminal domains.
Not available
S-EPMC11661193 | biostudies-literature
UnknownRegulatory Interactions between APOBEC3B N- and C-Terminal Domains.
Not available
S-EPMC12004528 | biostudies-literature
GenomicsDictyostelium discoideum
Deeply conserved gene-regulatory functions of carboxy-terminal domains in dictyostelid C-module-binding factors
PRJNA167805 | ENA
ProteomicsTripartite interactions of PKA catalytic subunit and C-terminal domains of cardiac Ca2+ channel may modulate its β-adrenergic regulation
The β-adrenergic augmentation of cardiac contraction, by increasing the conductivity of L-type voltage-gated CaV1.2 channels, is of great physiological and pathophysiological importance. Stimulation of β-adrenergic receptors (βAR) activates protein kinase A (PKA) through separation of regulatory (PK...
ORGANISM(S): Homo sapiens (Human) 
2024-11-22 | PXD057841 | Pride
Calcium channel  protein‐protein interaction  adrenergic regulation  cardiac  protein kinase a (pka)  heterologous expression 
TranscriptomicsFunctional analysis of TWIST1 domains regulating smooth muscle cell phenotype
TWIST1, a bHLH transcription factor, regulates mesenchymal specification, differentiation, proliferation and migration during development and in diseases such as cancer. More recently, genome-wide association studies have identified TWIST1 as a causal gene that increases risk for multiple vascular ...
ORGANISM(S): Homo sapiens 
2025-10-14 | E-MTAB-15722 | biostudies-arrayexpress
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