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MetabolomicsUntargeted lipidomics reveals colonic lipid alterations in C57BL/6J mice with acute Toxoplasma gondii infection

Although Toxoplasma gondii has been recognized as an obligate intracellular parasite, the lipid metabolic alterations it induces in colonic contents during acute infection remain poorly characterized. This study generated an acute infection model using C57BL/6J mice by oral inoculation with the T...

2026-09-10 | MTBLS15624 | MetaboLights
MetabolomicsA multi-omics dataset of C57 BL/6J mice regulated function by feed with ε-polylysine

The proteomic and metabolomic differences in mice fed ε-polylysine were detected by high-throughput sequencing and screening. The effects of ε-polylysine on the proteome and metabolomics of C57 BL/6J mice were studied. DIA proteome sequencing and liquid chromatography-mass spectrometry (LC-MS) we...

2025-04-14 | MTBLS4273 | MetaboLights
MetabolomicsMetabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice
It was recently demonstrated in mice that knockout of the flavin-containing monooxygenase 5 gene, Fmo5, slows metabolic ageing via pleiotropic effects. We have now used an NMR-based metabonomics approach to study the effects of ageing directly on the metabolic profiles of urine and plasma from male,...
2018-06-20 | MTBLS667 | MetaboLights
MetabolomicsSteam-exploded okara ameliorates hepatic lipid metabolism in high-fat diet-induced obese C57BL/6J mice: Evidence from multi-omics characterization

Okara, a byproduct of soybean processing, possesses valuable nutritional and physiological properties. Steam explosion, an efficient physical modification technique, can increase the soluble dietary fiber (SDF) content in okara and potentially amplify its health benefits, such as anti-obesity eff...

2025-10-23 | MTBLS13154 | MetaboLights
MetabolomicsThe gut microbiome has sexually dimorphic effects on bone tissue energy metabolism and multiscale bone quality in C57BL/6J mice
Not available
ORGANISM(S): Mus musculus 
ST002342 | MetabolomicsWorkbench
TranscriptomicsDietary folate depletion and repletion in C57BL/6J mice, ApoE knockout mice, and choline supplemented C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9243 | biostudies-arrayexpress
TranscriptomicsGenetic Determinants for Susceptibility to Staphylococcus aureus Infection in A/J and C57BL/6J
Although it has recently been shown that A/J mice are highly susceptible to Staphylococcus aureus sepsis as compared to C57BL/6J, the specific genes responsible for this differential phenotype are unknown. Using chromosome substitution strains (CSS), we found that factors on chromosomes (chr) 8, 11,...
ORGANISM(S): Mus musculus 
2010-08-01 | E-GEOD-19668 | biostudies-arrayexpress
TranscriptomicsDietary folate depletion and repletion in A/J and C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9242 | biostudies-arrayexpress
TranscriptomicsDietary folate depletion and repletion
This SuperSeries is composed of the following subset Series: GSE9242: Dietary folate depletion and repletion in A/J and C57BL/6J mice GSE9243: Dietary folate depletion and repletion in C57BL/6J mice, ApoE knockout mice, and choline supplemented C57BL/6J mice Keywords: SuperSeries Refer to individual...
ORGANISM(S): Mus musculus 
2010-06-20 | E-GEOD-9245 | biostudies-arrayexpress
MetabolomicsDietary ε-polylysine effects plasma metabolites profiling in mice

Dietary ε-polylysine effects on gut microbiota and plasma metabolites profiling in mice. Owing to the effect of ε-polylysine on microorganisms and phospholipid metabolism, we aimed to establish a comprehensive overview of microbial colonization affecting plasma glycerophospholipid metabolism in C...

2025-04-14 | MTBLS4270 | MetaboLights
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