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TranscriptomicsSingle cell RNA sequencing of LSK (lineage negative, Sca-1+, c-Kit+) cells isolated by fluorescence-activated cell sorting from the bone marrow of control young C57Bl/6Jax mice
Hematopoietic stem cells (HSCs) and different multipotent progenitor populations (MPPs) contained in the Lin- Sca-1+ c-Kit+ (LSK) compartment have previously been identified using diverse surface marker panels. However, a comprehensive and complete characterization of the complete LSK compartment is...
ORGANISM(S): Mus musculus 
2021-05-13 | E-MTAB-9208 | biostudies-arrayexpress
TranscriptomicsThe Global Molecular Landscape of dormant Hematopoietic Stem Cells
Rare dormant hematopoietic stem cells (dHSCs) reside at the top of the blood hierarchy harboring the highest long-term reconstitution capacity. However, no markers exist to prospectively identify dHSCs and their molecular identity, as well as the mechanism leading to their activation remains poorly ...
ORGANISM(S): Mus musculus 
2017-05-18 | E-MTAB-4547 | biostudies-arrayexpress
TranscriptomicsRNA Seq of control and Cyp26b1KO HSCs after 24h of in vitro culture and treatment
The transcriptome of Ctrl and Cyp26b1KO hematopoietic stem cells (HSC) after 24h in vitro culture upon retinoid treatment was assessed by RNAseq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-9752 | biostudies-arrayexpress
TranscriptomicsRNA Seq of wildtype and Rarb KO HSCs after 24h of in vitro culture and treatment
The transcriptome of WT and Rarb KO hematopoietic stem cells (HSC) after 24h in vitro culture upon retinoid treatment was assessed by RNAseq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-9749 | biostudies-arrayexpress
TranscriptomicsATAC-seq of control and Cyp26b1KO HSCs
The open chromatin of mouse control and Cyp26b1KO longterm hematopoietic stem cells has been profiled by ATAC-seq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-9778 | biostudies-arrayexpress
TranscriptomicsATAC-seq of HSCs in Vitamin A-free diet
The open chromatin of mouse longterm hematopoietic stem cells in control and vitamin A deficiency has been profiled by ATAC-seq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-9780 | biostudies-arrayexpress
TranscriptomicsATAC-seq of LT-HSCs and MPPs
The open chromatin of mouse longterm hematopoietic stem cells and multipotent progenitor cells has been profiled by ATAC-seq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-9779 | biostudies-arrayexpress
TranscriptomicsRNA Seq of 7-month old control and Cyp26b1KO LT-HSCs
The transcriptome of Ctrl and Cyp26b1KO longterm hematopoietic stem cells (LT-HSC) of 7-month old mice was assessed by RNAseq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-10659 | biostudies-arrayexpress
GenomicsChIPseq for H3K4me3 and H3K27me3 in LT-HSCs and MPPs
The distribution of H3K4- and H3K27me3 on the chromatin of mouse longterm hematopoietic stem cells and multipotent progenitor cells has been profiled by ChIP-seq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-10661 | biostudies-arrayexpress
TranscriptomicsRNA Seq of control and Cyp26b1 knockout mouse longterm hematopoietic stem cells
The transcriptome of Ctrl and Cyp26b1KO longterm hematopoietic stem cells (LT-HSC) was assessed by RNAseq.
ORGANISM(S): Mus musculus 
2021-11-02 | E-MTAB-9745 | biostudies-arrayexpress
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