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ProteomicsQuantitative proteomic analyses to reveal the key features of proteins in new onset Ankylosing spondylitis patients
Ankylosing spondylitis (AS) is a chronic immune-mediated disease. Various immune cells play an essential role in the AS pathogenesis. However, the specific pathogenesis of AS has not been well understood. Proteomic profiles of peripheral blood mononuclear cells (PBMCs) were applied to reveal the spe...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019667 | Pride
Ankylosing spondylitis  peripheral blood mononuclear cells  proteomic  phosphoromics 
ProteomicsMyeloid PTEN promotes chemotherapy-induced NLRP3 inflammasome activation and antitumor immunity
In this study, we found that myeloid PTEN can determine chemotherapy responsiveness by promoting NLRP3-dependent antitumor immunity and suggest that it might be a potential biomarker to predict the chemotherapy responses and manipulating NLRP3/IL-1might be able to overcome the chemotherapy resista...
ORGANISM(S): Homo Sapiens 
2020-04-16 | PXD018597 |
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