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TranscriptomicsInsights into N-calls of mitochondrial DNA sequencing using MitoChip v2.0
Background: Developments in DNA resequencing microarrays include mitochondrial DNA (mtDNA) sequencing and mutation detection. During automated analysis to sequence mtDNA, bases can be identified as wildtype, variant, or there may be a failure to assign a base (N-call) when compared to the mtDNA refe...
ORGANISM(S): Homo sapiens 
2012-05-17 | E-GEOD-29550 | biostudies-arrayexpress
TranscriptomicsEffect of TGF-M-NM-2 on gene expression of human prostate cancer cells PC-3
Transforming growth factor-M-NM-2 (TGF-M-NM-2) is a key factor for the development of prostate cancer metastases in bone. In breast cancer and melanoma, studies have shown how TGF-M-NM-2 regulates gene expression to allow cancer cells to adapt to the bone microenvironment. We used microarray analyse...
ORGANISM(S): Homo sapiens 
2014-11-01 | E-GEOD-58698 | biostudies-arrayexpress
MetabolomicsMulti-country metabolic signature discovery for chicken health classification

INTRODUCTION: To decrease antibiotic resistance, their use as growth promoters in the agricultural sector has been largely abandoned. This may lead to decreased health due to infectious disease or microbiome changes leading to gut inflammation.

OBJECTIVES: ...

2023-08-08 | MTBLS5065 | MetaboLights
TranscriptomicsGenome-wide haplotyping of human single cells
A method to infer genome-wide haplotypes from the analysis of one or two single (human) cells has tremendous applicative value. It would revolutionize not only preimplantation genetic diagnosis of in vitro fertilized human embryos in the clinic, but also animal breeding programs by enabling genome-w...
ORGANISM(S): Homo sapiens 
2012-10-01 | E-GEOD-17318 | biostudies-arrayexpress
UnknownSideways and stable crack propagation in a silicone elastomer.
Not available
S-EPMC6511042 | biostudies-literature
TranscriptomicsComparison of B. japonicum mutant strain M-NM-^T901 induced versus wild type uninduced
An initializing step in the rhizobia-legume symbiosis is the secretion of flavonoids by plants that leads to the expression of nodulation genes in rhizobia. Here we report the genome-wide transcriptional response of Bradyrhizobium japonicum to genistein, an isoflavone secreted by soybean. About 100 ...
ORGANISM(S): Bradyrhizobium japonicum 
2007-10-14 | E-GEOD-8570 | biostudies-arrayexpress
ProteomicsProfiling antibody responses to M. tuberculosis proteins in TB suspects’ sera using full-proteome microarrays.
Understanding the immune response to tuberculosis requires greater knowledge of humoral responses. To characterize antibody targets and the effect of disease parameters on target recognition, we developed a systems immunology approach that integrated detection of antibodies against the entire Mycob...
ORGANISM(S): Homo sapiens 
2010-07-13 | E-GEOD-19433 | biostudies-arrayexpress
UnknownCharacterization of Interactions between CTX-M-15 and Clavulanic Acid, Desfuroylceftiofur, Ceftiofur, Ampicillin, and Nitrocefin.
Not available
S-EPMC9100253 | biostudies-literature
TranscriptomicsFrequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours
Inflammatory hepatocellular adenomas (IHCA) are benign liver tumours defined by the presence of inflammatory infiltrates and by the elevated expression of inflammatory proteins in tumour hepatocytes1,2. Here we show a striking activation of the IL6 signalling pathway in this tumour type, and sequenc...
ORGANISM(S): Homo sapiens 
2008-12-24 | E-GEOD-11819 | biostudies-arrayexpress
UnknownAncient mitochondrial M haplogroups identified in the Southwest Pacific.
Not available
S-EPMC1201611 | biostudies-literature
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