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TranscriptomicsCaM Kinase II mediates maladaptive post-infarct remodeling but not acute myocardial ischemia/reperfusion injury
Calcium/calmodulin-dependent protein kinase II (CaMKII) was suggested to mediate ischemic myocardial injury and adverse cardiac remodeling. However, the specific functions of the CaMKII isoforms and splice variants in ischemia/reperfusion (I/R) injury have not been investigated yet. Thus, we studied...
ORGANISM(S): Mus musculus 
2014-09-08 | E-GEOD-58486 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CALM-AF10 positive and negative T-ALL samples
Comparison of a series of 6 CALM-AF10 positive T-ALL to a series of 17 CALM-AF10 negative T-ALL
ORGANISM(S): Homo sapiens 
2007-08-30 | E-GEOD-2117 | biostudies-arrayexpress
TranscriptomicsLong-term Exposure to Sorafenib of Liver Cancer Cells Induces Resistance with Epithelial-to-Mesenchymal Transition, Increased Invasion and Risk of Rebound Growth
Sorafenib leads to a survival benefit in patients with advanced hepatocellular carcinoma but its use is hampered by the occurrence of drug resistance. To investigate the molecular mechanisms involved we developed five resistant human liver cell lines in which we studied morphology, gene expression a...
ORGANISM(S): Homo sapiens 
2016-03-14 | E-GEOD-62813 | biostudies-arrayexpress
TranscriptomicsBmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis [telogen].
While several physiological skin parameters vary in a circadian manner, the identity of genes participating in chronobiology of skin remains unknown, leading us to define the circadian transcriptome of mouse skin at two different stages of the hair cycle, telogen and anagen. The circadian transcrip...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-38622 | biostudies-arrayexpress
TranscriptomicsBmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis [Bmal1 KO]
While several physiological skin parameters vary in a circadian manner, the identity of genes participating in chronobiology of skin remains unknown, leading us to define the circadian transcriptome of mouse skin at two different stages of the hair cycle, telogen and anagen. The circadian transcrip...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-38624 | biostudies-arrayexpress
TranscriptomicsBmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis [Anagen]
While several physiological skin parameters vary in a circadian manner, the identity of genes participating in chronobiology of skin remains unknown, leading us to define the circadian transcriptome of mouse skin at two different stages of the hair cycle, telogen and anagen. The circadian transcrip...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-38623 | biostudies-arrayexpress
TranscriptomicsBmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis
This SuperSeries is composed of the following subset Series: GSE38622: Bmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis [telogen]. GSE38623: Bmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epider...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-38625 | biostudies-arrayexpress
ProteomicsChapman_CCM_2018
This submission contains the mass spectrometry files for the manuscript by Chapman and colleagues that characterize KRI-1 in C. elegans by affinity purification experiments of KRI-1 fused to GFP. Controls used for this experiment include ACT-5 fused to GFP and N2 worms. This dataset consists of 18 ...
ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239) 
2018-05-24 | MSV000082400 | MassIVE
TranscriptomicsTranscription profiling of neonatal rat ventricular myocytes treated with phenylephrine or PAMH
Neonatal rat ventricular myocytes cultured for 48 hours without stimulation, in the presence of twenty micromolar phenylephrine, or in the presence of one micromolar PAMH.
ORGANISM(S): Rattus norvegicus 
2008-06-16 | E-GEOD-925 | biostudies-arrayexpress
TranscriptomicsGene expression data from HCC4006 and HCC4006ER cells
We generated erlotinib-resistant HCC4006 cells (HCC4006ER) by chronic exposure of EGFR-mutant HCC4006 cells to increasing concentrations of erlotinib. HCC4006ER cells acquired an EMT phenotype and activation of the TGF-β/SMAD pathway, while lacking both T790M secondary EGFR mutation and MET gene amp...
ORGANISM(S): Homo sapiens 
2015-07-31 | E-GEOD-71587 | biostudies-arrayexpress
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