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GenomicsThe Hippo tranducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation
The Hippo pathway effector YAP1 controls stem cell fate in epithelial tissues, but its role in stem cells of non-epithelial tissues, such as skeletal muscle, is poorly documented. Here we show that sustained YAP1 activity in mouse activated satellite cells in vivo induces rhabdomyosarcoma (RMS) rese...
ORGANISM(S): Homo sapiens 
2014-08-12 | E-GEOD-55186 | biostudies-arrayexpress
TranscriptomicsGene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma (Training Set, Liver)
Background: It is a challenge to identify those patients who, after undergoing potentially curative treatments for hepatocellular carcinoma, are at greatest risk of recurrence. Such high-risk patients could receive novel interventional measures. An obstacle to the development of genome-based predict...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-10140 | biostudies-arrayexpress
TranscriptomicsGene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma (Training Set, HCC)
Background: It is a challenge to identify those patients who, after undergoing potentially curative treatments for hepatocellular carcinoma, are at greatest risk of recurrence. Such high-risk patients could receive novel interventional measures. An obstacle to the development of genome-based predict...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-10141 | biostudies-arrayexpress
TranscriptomicsGene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma (Validation Set)
Background: It is a challenge to identify those patients who, after undergoing potentially curative treatments for hepatocellular carcinoma, are at greatest risk of recurrence. Such high-risk patients could receive novel interventional measures. An obstacle to the development of genome-based predict...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-10142 | biostudies-arrayexpress
TranscriptomicsGene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma
Background: It is a challenge to identify those patients who, after undergoing potentially curative treatments for hepatocellular carcinoma, are at greatest risk of recurrence. Such high-risk patients could receive novel interventional measures. An obstacle to the development of genome-based predict...
ORGANISM(S): Homo sapiens 
2010-05-20 | E-GEOD-10143 | biostudies-arrayexpress
TranscriptomicsIntegrative Transcriptome Analysis Reveals Common Molecular Subtypes of Human Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, and prior attempts to develop genomic-based classification for HCC have yielded highly divergent results, indicating difficulty in identifying unified molecular anatomy. We performed a meta-analysis of gene expression profiles in data...
ORGANISM(S): Homo sapiens 
2009-09-08 | E-GEOD-10186 | biostudies-arrayexpress
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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