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ProteomicsQuantitative profiling of the enzymatic activity of the protein lysine mono-methyltransferase SMYD2 using SILAC-based proteomics
The significance of non-histone lysine methylation in cell biology and human disease is an emerging area of research exploration, and small molecule inhibitors that selectively and potently target “writers” and “erasers” of methyl-lysine, such as the protein lysine mono-methyltransferase SMYD2, are ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080785 | MassIVE
UnknownWeight loss after Roux-En-Y gastric bypass surgery reveals skeletal muscle DNA methylation changes.
Not available
S-EPMC8088644 | biostudies-literature
UnknownRisk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening.
Not available
S-EPMC4463475 | biostudies-literature
ProteomicsIdentifying altered mouse gephyrin interactome after sleep deprivation
GABAergic transmission controls cortical sleep, however the molecular determinants of GABAergic control of this phenomenon are unknown. We used immunoprecipitation of the inhibitory postsynaptic protein gephyrin to identify gephyrin interactors at ZT6 (sleep) and ZT6 with sleep deprivation (ZT6SD).
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD048929 | Pride
Mouse Gephyrin interactome Sleep deprivation 
UnknownPotential epigenetic biomarkers of obesity-related insulin resistance in human whole-blood.
Not available
S-EPMC5398771 | biostudies-literature
ProteomicsQuantitative profiling of the enzymatic activity of the protein lysine mono-methyltransferase SMYD2 using SILAC-based proteomics
The significance of non-histone lysine methylation in cell biology and human disease is an emerging area of research exploration, and small molecule inhibitors that selectively and potently target “writers” and “erasers” of methyl-lysine, such as the protein lysine mono-methyltransferase SMYD2, are ...
ORGANISM(S): Homo sapiens (Human) 
2016-01-11 | PXD002405 | Pride
Methylation Lysine methyltransferase Silac Immunoaffinity enrichment Smyd2 
UnknownGenetic architecture reconciles linkage and association studies of complex traits.
Not available
S-EPMC11835202 | biostudies-literature
UnknownPrevalence of Celiac Disease in 52,721 Youth With Type 1 Diabetes: International Comparison Across Three Continents.
Not available
S-EPMC6463736 | biostudies-literature
UnknownThe Contemporary Prevalence of Diabetic Neuropathy in Type 1 Diabetes: Findings From the T1D Exchange.
Not available
S-EPMC7085805 | biostudies-literature
GenomicsTRACERx: TRAcking non-small cell lung Cancer Evolution through therapy (Rx). Pilot Study. Multi-region sequencing of early-stage NSCLCs.
Deciphering the complexity of non-small cell lung cancer (NSCLC) evolutionary histories may elucidate the basis for its dismal outcome. We performed multi-region sequencing of early-stage NSCLCs. Spatial dissection revealed branched tumor evolution, with driver mutations occurring before and after s...
EGAS00001000809 | EGA
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