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Proteomics4-HNE modification of human recombinant Dicer
We used mass spectrometry analysis (nanoLC-MS/MS) to map 4-HNE-modified residues of human Dicer exposed in vitro to 4-HNE in a concentration-dependent maner
ORGANISM(S): Homo sapiens (Human) 
2023-11-17 | PXD034113 | Pride
Human dicer 4-hne Lc-ms/ms 
TranscriptomicsGenome-wide copy number analysis of patient-derived gliobastoma cell cultures
Genome-wide copy number variation profiles were analyzed in the patient-derived gliobastoma cell culture samples. For this purpose, gDNA was analyzed using the CytoScan® assay in combination with a one-color based labeling and hybridization protocol. Signals on the CytoScan® HD microarrays were dete...
ORGANISM(S): Homo sapiens 
2019-02-28 | E-MTAB-7649 | biostudies-arrayexpress
MetabolomicsProtein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights
ProteomicsOxygen Toxicity Causes Cyclic Damage by Destabilizing Specific Fe-S Cluster-Containing Protein Complexes
Oxygen is toxic across all three domains of life. Yet, the underlying molecular mechanisms remain largely unknown. Here, we systematically investigate the major cellular pathways affected by excess molecular oxygen. We find that hyperoxia destabilizes a specific subset of Fe-S cluster (ISC)-containi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-02-05 | MSV000091206 | MassIVE
UnknownA second update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC10482689 | biostudies-literature
UnknownThe Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.
Not available
S-EPMC6075733 | biostudies-literature
UnknownComparative Molecular Analysis of Gastrointestinal Adenocarcinomas.
Not available
S-EPMC5966039 | biostudies-literature
UnknownFuture-proofing and maximizing the utility of metadata: The PHA4GE SARS-CoV-2 contextual data specification package.
Not available
S-EPMC8847733 | biostudies-literature
UnknownCell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.
Not available
S-EPMC5957518 | biostudies-literature
UnknownMapping the human genetic architecture of COVID-19.
Not available
S-EPMC8674144 | biostudies-literature
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