Cancer-associated fibroblast

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Transcriptomics (2271)
Unknown (2036)
Genomics (657)
Proteomics (181)
Other (24)
Methylation profiling (10)
Metabolomics (9)
Models (5)
Genomic (1)
Multiomics (1)

Organisms

Homo sapiens (1619)
Mus musculus (655)
Rattus norvegicus (28)
Drosophila melanogaster (14)
Sus scrofa (13)
Arabidopsis thaliana (13)
Saccharomyces cerevisiae (11)
Bos taurus (10)
Danio rerio (10)
Gallus gallus (8)
Streptococcus pneumoniae D39 (7)
Canis lupus familiaris (5)
Macaca mulatta (4)
Zea mays (3)
Schizosaccharomyces pombe (3)
Oryza sativa Japonica Group (3)
Caenorhabditis elegans (3)
Boehmeria nivea (2)
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 (2)
Musa acuminata (2)
Aspergillus flavus (2)
Brugia pahangi (2)
Equus caballus (2)
Oryza sativa Indica Group (2)
Macaca fascicularis (2)
Campylobacter jejuni (2)
Oryza sativa (2)
Hordeum vulgare (2)
Oncorhynchus mykiss (2)
Ovis aries (2)

Organisms

Homo sapiens (294)
Mus musculus (133)
human metagenome (1)
Canis lupus familiaris (1)
Rattus norvegicus (1)

Repository

biostudies-arrayexpress (2007)
ENA (497)
geo (407)
pride (107)
EGA (60)
MassIVE (41)
iProX (11)
MetaboLights (9)
jPOST (8)
BioModels (3)
Cell Collective (2)
EVA (2)
GPMDB (2)
ExpressionAtlas (1)
dbGaP (1)

Tissue

Fibroblast (72)
Cell culture (35)
Epithelial cell (15)
Breast (12)
Colon (6)
Lung (5)
Permanent cell line cell (5)
Primary cell (5)
Skin (5)
Embryo (3)
Melanocyte (3)
Mesothelial fibroblast (3)
Pleural mesothelium (3)
Stromal cell (3)
T cell (3)
B cell (2)
Blood (2)
Brain (2)
Early embryonic cell (2)
Fibroblast of lung (2)
Lung epithelium (2)
Macrophage (2)
Myeloid suppressor cell (2)
Neutrophil (2)
Ovary cancer cell (2)
Pancreas (2)
Platelet (2)
Stem cell (2)
Blood cell (1)
HMVEC cell (1)

Disease

Breast cancer (24)
Normal (11)
Pancreatic ductal adenocarcinoma (4)
Colon cancer (4)
Malignant neoplasm of ovary (4)
Melanoma (4)
Glioblastoma (3)
Glioblastoma multiforme (3)
Colorectal cancer (3)
Adenocarcinoma (2)
Not Available (2)
Control (1)
Testicular seminoma (1)
GIP-dependent Cushing's syndrome (1)
HPV positive (1)
Osteosarcoma subtype fibroblastic (1)
High grade glioblastoma (1)
Primary effusion lymphoma (PEL) (1)
Diffuse large B-cell lymphoma (1)
Chronic pancreatitis (1)
AIDS-KS, HIV+, nodular (late) stage (1)
Basal cell carcinoma, Gorlin-Goltz syndrome (1)
Bladder cancer (1)
Tumour (1)
Giant Cell Glioblastoma (1)
Cancer (1)
Renal cell carcinoma (1)
Prostate cancer (1)
Breast carcinoma (1)
Neurofibromatosis type 1 (1)

Technology Type

Mass Spectrometry (107)
Shotgun proteomics (79)
Bottom-up proteomics (19)
Data-independent acquisition (9)
Data-dependent acquisition (7)
Affinity purification coupled with mass spectrometry proteomics (6)
Gel-based experiment (6)
Mass spectrometry (5)
ILLUMINA, Illumina HiSeq 2500 (3)
Illumina HiSeq 2000 (3)
NMR spectroscopy (2)
Mass spectrometry assay (2)
DiaPASEF (2)
SWATH MS (2)
Top-down proteomics (2)
Illumina HiSeq 2000, HiSeq X Ten, Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiSeq 4000, ILLUMINA (1)
Illumina HiSeq 2000, Affymetrics_SNP_6.0-, Illumina Genome Analyzer IIx (1)
ILLUMINA, Illumina HiSeq 2000 (1)
Illumina HiSeq 2000, ILLUMINA, Illumina HiSeq 2500 (1)

Instrument Platform

Illumina NovaSeq 6000 (26)
Illumina HiSeq 2500 (15)
Illumina HiSeq 4000 (12)
NextSeq 500 (11)
NextSeq 550 (6)
Illumina NovaSeq X (5)
NextSeq 2000 (5)
Illumina HiSeq 2000 (5)
Illumina MiSeq (4)
DNBSEQ-G400 (3)
Bio-Rad CFX96 Real-time System (2)
Illumina HiSeq 1500 (2)
NextSeq 550 (Illumina). (1)
Nikon Eclipse Ti2 with brightfield and fluorescence capacity (TRITC) (1)
Leica Biosystems Cryostat (1)
Agilent TapeStation 4200 (1)
10x Chromium v3 (1)
BD LSRFortessa (1)
MACS Whole Skin Dissociation Kit (1)
G2565BA DNA microarray scanner (1)
Agilent 2100 Bioanalyzer, Applied Biosystems 7900HT Sequence Detection System, Illumina TruSeq Small RNA Sample Preparation Kit (1)
RNeasy mini Kit, Ribo-Zero Human/Mouse/Rat kit (1)
DNA 7500 Bioanalyzer Chips (1)
Qubit instrument, DNA HS kit (1)
High Sensitivity DNA kit (1)
BioRad SureCell (1)
Axon Instruments GenePix 4000B scanner (1)
Solexa 2G Genome Analyzer (1)
IScan Illumina (1)
Unspecified (1)

Publication Date

2010 (299)
2015 (287)
2013 (281)
2014 (240)
2012 (224)
2011 (221)
2016 (122)
2008 (110)
2026 (105)
2025 (93)
2009 (90)
2024 (88)
2023 (70)
2022 (66)
2021 (63)
2020 (47)
2019 (44)
2007 (40)
2018 (32)
2005 (22)
2017 (21)
2006 (20)
2004 (6)
2003 (1)
2002 (1)
2027 (1)

UNIPROT ID/AC

P47811 (2)
O09110 (2)
P70236 (2)
Q9WUB0 (2)
Q91WA6 (2)
Q924T7 (2)
Q62073 (2)
Q60855 (2)
P70191 (2)
Q9WTK5 (2)
P39429 (2)
Q3U0V2 (2)
P25118 (2)
P70196 (2)
P25799 (2)
Q9Z1E3 (2)
Q9WTU6 (1)
Q91Y86 (1)
Q8CE90 (1)
P47809 (1)
Q99K90 (1)
Q571K4 (1)
Q8CF89 (1)
P05121 (1)
Q969D9 (1)
P13501 (1)
P42768 (1)
Q13480 (1)
P22692 (1)
P53779 (1)

CHEBI ID

CHEBI:15741 (3)
CHEBI:32816 (3)
CHEBI:137155 (2)
CHEBI:134239 (2)
CHEBI:134451 (2)
CHEBI:134270 (2)
CHEBI:141588 (2)
CHEBI:71729 (2)
CHEBI:64433 (2)
CHEBI:16113 (2)
CHEBI:15611 (2)
CHEBI:15428 (2)
CHEBI:17148 (2)
CHEBI:17015 (2)
CHEBI:30746 (2)
CHEBI:17821 (2)
CHEBI:17154 (2)
CHEBI:16196 (2)
CHEBI:7916 (2)
CHEBI:17203 (2)
CHEBI:16104 (2)
CHEBI:422 (2)
CHEBI:17053 (2)
CHEBI:15366 (2)
CHEBI:16027 (2)
CHEBI:30915 (2)
CHEBI:139356 (1)
CHEBI:64297 (1)
CHEBI:30413 (1)
CHEBI:33699 (1)

Metabolite Name

Benzoate (2)
L-Lactic acid (2)
Pyruvic acid (2)
Glycine (2)
Thymine (2)
Niacinamide (2)
L-Aspartic acid (2)
L-Proline (2)
Succinic acid (2)
Cholesterol (2)
Sarcosine (2)
Riboflavin (2)
L-Valine (2)
L-Isoleucine (2)
L-Tyrosine (2)
Hypoxanthine (2)
PI(39:6) (1)
PS(36:0) (1)
PI(35:1) (1)
PS(33:1) (1)
PE(34:1) (1)
PI(39:5) (1)
PE(36:1) (1)
CerP(d15:0/12:0) (1)
CerP(d15:0/10:0) (1)
PEp 38:4-A (1)
PE 40:6-B (1)
PE 38:6-A (1)
PG 38:5 (1)
PS 34:0 (1)

First Public Date

2026 (94)
2025 (76)
2024 (63)
2023 (45)
2014 (40)
2020 (38)
2022 (36)
2021 (36)
2019 (22)
2018 (13)
2015 (13)
2017 (9)
2016 (6)
2013 (6)

Modelling Approach

Ordinary differential equation model (2)
Boolean model (1)

Lab affiliation

University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (13)
CRUK Beatson Institute (4)
CRUK - Beatson Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (3)
CRUK Scotland Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (2)
Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete (2)
Merck & Co., Inc. (2)
Moffitt Cancer Center Tampa, FL, USA (2)
1INSERM, U1068, Cancer Research Center of Marseille, Institut Paoli-Calmettes, CNRS, UMR7258, and University Aix-Marseille, Marseille, France (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technical University Munich (TUM) Gregor-Mendel-Strasse 4 85354 Freising GERMANY (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) School of Life Sciences Technical University Munich (TUM) Gregor-Mendel-Straße 4 85354 Freising GERMANY Bavarian Center for Biomolecular Mass Spectrometry Technische Universität München Gregor-Mendel-Straße 4 85354 Freising DEUTSCHLAND / GERMANY (1)
Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark (1)
Boston University (1)
Boston University Chobanian & Avedisian School of Medicine Department of Pathology & Laboratory Medicine (1)
CIB-CSIC (Spanish Research Council) (1)
CRUK & MRC Oxford Institute for Radiation Oncology, University of Oxford, Department of Oncology, Old Road Campus Research Building, Oxford, OX37DQ, UK (1)
CRUK - Scotland Institute - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (1)
Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver V5Z 1L3, Canada. (1)
Cancer Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, 3800, Australia (1)
Cancer Research UK Manchester Institute Systems Oncology (1)
Centre for Cancer Biology, SA Pathology and the University of South Australia, Adelaide SA 5000, Australia (1)
Centre for Haemato-oncology, Barts Cancer Institute, Queen Mary University of London, London, EC1M6BQ, UK (1)
Chair in Translational Cancer Research, NHMRC Clinical Trials Centre, University of Sydney, Australia. NH&MRC Senior Principal Research Fellow. Deputy Director, Centenary Institute. Deputy Director, Sydney Catalyst. Head, ACRF Centenary Cancer Research Centre. (1)
Chemical & Biomolecular Engineering, Johns Hopkins University (1)
Department of Anatomy and Cell Biology, Université de Sherbrooke (1)
Department of Biochemistry, University of Turku, Turku, FINLAND (1)
Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631 (1)
Department of Biology, University of Fribourg, Chemin du Musée 10, 1700 Fribourg, Switzerland (1)
Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel. (1)
Department of Innovative Technologies in Medicine & Dentistry, University of Chieti, Italy (1)
Department of Innovative Technologies in Medicine and Dentistry,University “G. d’Annunzio” of Chieti-Pescara, Italy (1)

IsPrivate

False (3)

Submitter Keywords

Not Peer Reviewed (1)

Study type

Transcription profiling by array (1440)
RNA-seq of coding RNA (202)
Unknown experiment type (59)
ChIP-seq (47)
Methylation profiling by array (45)
Comparative genomic hybridization by array (34)
RNA-seq of non coding RNA (32)
RNA-seq of coding RNA from single cells (25)
ChIP-chip by tiling array (20)
Other (18)
Transcription profiling by RT-PCR (13)
Proteomic profiling by array (13)
Genotyping by array (10)
Transcription profiling by SAGE (9)
Methylation profiling by high throughput sequencing (5)
RNAi profiling by array (4)
ChIP-chip by array (4)
Human - High-throughput sequencing (3)
Transcription profiling by tiling array (3)
Spatial transcriptomics by high-throughput sequencing (3)
DNA-seq (3)
High-throughput sequencing (2)
Cell line - High-throughput sequencing (2)
MicroRNA profiling by high throughput sequencing (2)
RNA-seq of total RNA (2)
Cell line - Methylation microarray (1)
Differential (1)
Human - Single-cell sequencing (1)
Proteomic profiling by mass spectrometer (1)
ATAC-seq (1)

Release Date

2015 (339)
2010 (312)
2013 (303)
2022 (285)
2025 (278)
2023 (269)
2014 (266)
2011 (240)
2012 (236)
2021 (229)
2024 (228)
2016 (196)
2020 (146)
2019 (129)
2008 (117)
2009 (106)
2018 (103)
2017 (98)
2026 (65)
2007 (41)
2005 (23)
2006 (22)
2004 (7)
2003 (1)
2002 (1)
2001 (1)
2000 (1)
1999 (1)

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Characterization of various cell lines from different ampullary cancer subtypes and cancer associated fibroblast-mediated responses

Introduction: Ampullary cancer is a relatively rare entity and usually treated by pancreatoduodenectomy followed by adjuvant therapy. The intestinal subtype is associated with markedly improved prognosis after resection. Only few cell lines are available for in vitro studies of ampullary cancer and ...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2017-03-29 | MSV000080802 | MassIVE

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - ZR-75-1 breast cancer cells

Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079958 | MassIVE

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - tumor-distant tissue sections

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079950 | MassIVE

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - primary mammary fibroblasts treated with IL1-beta

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079966 | MassIVE

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - primary mammary fibroblasts treated with TGF-beta

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079968 | MassIVE

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - primary mammary fibroblasts

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079940 | MassIVE

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - bulk tumor tissue

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079947 | MassIVE

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts.

Data from ProteomeXchange, PXD ID: PXD001324. Experiment: P1, file: P1_Cyt_Near_4.mzml. Published as part of J Proteome Res. 2014 Sep 19. . From the Abstract: {{i}} Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-a...

ORGANISM(S): Homo_sapiens_viruses, Human_female

GPM11210030024 | GPMDB

Resource Reanalysis

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts.

Data from ProteomeXchange, PXD ID: PXD001323. Experiment: hmf_cyt_TGFb_1, file: hmf_cyt_TGFb_1_2.mzml. Published as part of J Proteome Res. 2014 Sep 19. . From the Abstract: {{i}} Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attribu...

ORGANISM(S): Homo_sapiens_viruses, Human_female

GPM32320003614 | GPMDB

Resource Reanalysis

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - tumor-near tissue sections

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079953 | MassIVE

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