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To further investigate the molecular mechanisms by which EVs mediated the abnormal localization of tight junction proteins and adherence junction protein, we performed miRNA microarray analysis of extracellular vesicles isolated from breast cancer cells. miRNA expression in extracellular vesicles wa...
ORGANISM(S): Homo sapiens 
To investigate the mRNA expression after extracellular vesicles or miRNA treatement, global gene expression analysis was performed in endothelial cells after the transfection of N.C. or miR-181c and or after the addition of extracellular vesicles from cancer cells. mRNA expression in brain endotheli...
ORGANISM(S): Macaca fascicularis 
Osteolineage cells represent one of the critical bone marrow niche components that support maintenance of hematopoietic stem and progenitor cells (HSPCs). Recent studies demonstrate that extracellular vesicles (EVs) regulate stem cell development via horizontal transfer of bioactive cargo, including...
ORGANISM(S): Homo sapiens 
Beyond forming bone, osteoblasts play pivotal roles in various biological processes, including hematopoiesis and bone metastasis. Extracellular vesicles (EVs) have recently been implicated in intercellular communication via transfer of proteins and nucleic acids between cells. Here, we focused on th...
ORGANISM(S): Homo sapiens 
In-depth (phospho)proteome characterization of breast cancer derived extracellular vesicles (EVs).
ORGANISM(S): Homo sapiens (Human) 
2019-10-24 | PXD012162 | Pride
Freshly resected colorectal cancer tissues and adjacent normal tissues of 17 individuals were incubated in serum-free medium. Extracellular vesicles were isolated from the medium with ultracentrifugation method.
ORGANISM(S): Homo Sapiens (human) 
Gene expression profiles were generated using RNA-sequencing from migratory and non-migratory B-cells after exposure to conditioned medium of breast cancer cells, either containing or depleted from extracellular vesicles. The purpose of the experiment was to investigate how breast cancer cell derive...
ORGANISM(S): Homo sapiens 
In this study, we employed proteomic analysis to gain deeper insights into the role of EVs in breast adiponcosis, providing novel evidence on the role of adipocyte-derived EVs in sustaining mitochondrial metabolism in breast cancer cells.
ORGANISM(S): Homo sapiens (Human) 
2025-10-27 | PXD059789 | Pride
Exosomal microRNA signature from plasma-derived extracellular vesicles in gastric cancer
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