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TranscriptomicsTranscriptional landscape of Candida parapsilosis
We used next generation sequencing (RNA-seq) to determine the transcriptional profile of C. parapsilosis growing in several conditions including different media, temperatures and oxygen concentrations. We have 37 Samples representing BMW and YPD media, 1% and 21% oxygen, 30 and 37 degree celsius tem...
ORGANISM(S): Candida parapsilosis 
2011-11-30 | E-GEOD-32714 | biostudies-arrayexpress
MetabolomicsMetabolic profiling of Candida clinical isolates of different species and infection sources

Candida species are the most common cause of opportunistic fungal infections. Rapid identification and novel approaches for the characterization of these fungi are of great interest to improve the diagnosis and the knowledge about their pathogenic properties. This study aimed to characte...

2024-07-09 | MTBLS1978 | MetaboLights
TranscriptomicsHypoxia and biofilms in Candida parapsilosis
This SuperSeries is composed of the following subset Series: GSE13717: Transcriptional profile of Candida parapsilosis in SD media GSE13722: Transcriptional response of Candida parapsilosis in low oxygen (hypoxic) conditions in SD media Refer to individual Series
ORGANISM(S): Candida parapsilosis 
2010-05-06 | E-GEOD-13832 | biostudies-arrayexpress
MetabolomicsRapid Evaporative Ionisation Mass Spectrometry (REIMS) Provides Accurate Direct from Culture Species Identification within the Genus Candida
Members of the genus Candida, such as C. albicans and C. parapsilosis, are important human pathogens. Other members of this genus, previously believed to carry minimal disease risk, are increasingly recognised as important human pathogens, particularly because of variations in susceptibilities to wi...
2017-11-01 | MTBLS383 | MetaboLights
TranscriptomicsAnalysis of the transcriptional response of Candida parapsilosis following exposure to farnesol
We used the results of a genome sequence survey to design and manufacture partial genomic microarrays that were applied to determining the transcriptional response of C. parapsilosis to the presence of exogenous farnesol. Keywords: drug response, farnesol, Transcriptional profiling was performed fo...
ORGANISM(S): Candida parapsilosis 
2010-06-11 | E-GEOD-6318 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of Candida parapsilosis in low oxygen (hypoxic) conditions in SD media
Whole genome microarray was used to compare the transcriptional profile of C. parapsilosis growing in normoxic (21% oxygen) and hypoxic (1% oxygen) conditions. RNA was isolated from cells grown in SD media at 37°C for 3 h in atmosphere oxygen of 1% oxygen, and labeled with Cy5 or Cy3. Six independe...
ORGANISM(S): Candida parapsilosis 
2010-05-06 | E-GEOD-13722 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of an azole-resistant Candida parapsilosis isolate [posaconazole].
Azole resistance was induced in vitro by growth of a susceptible C. parapsilosis isolate in the presence of posaconazole. Whole genome microarrays were used to compare the transcriptional response of the posaconazole-resistant and susceptible isolates. Transcriptional profile of an in vitro derived ...
ORGANISM(S): Candida parapsilosis 
2011-04-18 | E-GEOD-27407 | biostudies-arrayexpress
TranscriptomicsTranscriptional landscape of the pathogenic yeast Candida parapsilosis
This SuperSeries is composed of the following subset Series: GSE32712: Transcriptional profile of Candida parapsilosis CLIB214 21% Oxygen (normoxia) versus at 1% oxygen (hypoxia). GSE32713: Transcriptional profile of Candida parapsilosis CLIB214 versus UPC2 delete, both at 1% oxygen (hypoxia) GSE3...
ORGANISM(S): Candida parapsilosis 
2011-11-30 | E-GEOD-32716 | biostudies-arrayexpress
TranscriptomicsComparative phenotypic analysis of the major fungal pathogens Candida parapsilosis and Candida albicans
Abstract: Candida parapsilosis and Candida albicans are human fungal pathogens that belong to the CUG clade in the Saccharomycotina. In contrast to C. albicans, relatively little is known about the virulence properties of C. parapsilosis, a pathogen particularly associated with infections of prematu...
ORGANISM(S): Candida parapsilosis 
2014-07-21 | E-GEOD-57451 | biostudies-arrayexpress
TranscriptomicsConserved and divergent roles of Bcr1 and CFEM proteins in Candida parapsilosis and Candida albicans
This SuperSeries is composed of the following subset Series: GSE33460: Transcriptional profile of Candida albicans bcr1 knockout. GSE33461: Transcriptional profile of Candida parapsilosis bcr1 knockout. GSE33462: Transcriptional profile of Candida parapsilosis CLIB214 culture in low iron conditions ...
ORGANISM(S): Candida parapsilosis 
2011-11-05 | E-GEOD-33490 | biostudies-arrayexpress
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