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MetabolomicsLung Lipidomic Alterations in Beagle Dogs Infected with Toxocara canis

Toxocariasis, mainly caused by Toxocara canis, and to a lesser extent, Toxocara cati, is a neglected parasitic zoonosis. The mechanisms that underlie the changes in lipid metabolism of T. canis infection in Beagle dogs' lungs remain unclear. Lipidomics is a rapidly emer...

2023-08-21 | MTBLS5583 | MetaboLights
MetabolomicsLipidomic Changes in the Liver of Beagle Dogs Associated with Toxocara canis Infection

In this study, lipid alterations in Beagle dog’s liver caused by Toxocara canis infection were investigated by using liquid chromatography with tandem mass spectrometry at 12 hours post infection (hpi), 24 hpi and 36 days post infection (dpi). A total of 6 categories and 42 subclasses of...

2022-08-30 | MTBLS4015 | MetaboLights
ProteomicsAnalysis of the Babesia canis secreted proteome during virulent infection
Secreted parasite factors from Babesia canis during acute infection were investigated using a LC-MS/MS assay which led to the discovery of potential pathogenicity factors. Combined data from genomics, transcriptomics and proteomics provide a first predicted and partially validated set of potential v...
ORGANISM(S): Babesia canis canis Babesia canis 
2017-06-16 | PXD005117 | Pride
Canine babesiosis Pathogenicity factors Shot-gun ms Babesia canis Secretome 
ProteomicsProteomics and bioinformatics investigations to improve serological diagnosis of canine brucellosis
Brucella canis is pathogenic for dogs and humans. Serological diagnosis is a cost-effective approach for disease surveillance, but a major drawback of current serological tests is the cross-reactivity with other bacteria that results in false positive reactions, and development of indirect tests wit...
ORGANISM(S): Brucella canis ATCC 23365 
2023-10-24 | PXD042682 | Pride
Brucella canis  western blotting  mass spectrometry  protein identification Bioinformatics 
TranscriptomicsDifferential Expression of Iron Acquisition Genes by Brucella melitensis and Brucella canis During Macrophage Infection (part 2)
Brucella melitensis and Brucella canis differ by ~75 genes yet B. melitensis is highly virulent for humans while B. canis is considered rarely pathogenic. No identified bacterial factors or mechanisms account for this difference in virulence. To identify functional differences of these two bacteri...
ORGANISM(S): Brucella canis 
2012-12-01 | E-GEOD-34498 | biostudies-arrayexpress
TranscriptomicsDifferential Expression of Iron Acquisition Genes by Brucella melitensis and Brucella canis During Macrophage Infection (part 4)
Brucella melitensis and Brucella canis differ by ~75 genes yet B. melitensis is highly virulent for humans while B. canis is considered rarely pathogenic. No identified bacterial factors or mechanisms account for this difference in virulence. To identify functional differences of these two bacteri...
ORGANISM(S): Brucella canis 
2012-12-01 | E-GEOD-34503 | biostudies-arrayexpress
TranscriptomicsDifferential Expression of Iron Acquisition Genes by Brucella melitensis and Brucella canis During Macrophage Infection (part 3)
Brucella melitensis and Brucella canis differ by ~75 genes yet B. melitensis is highly virulent for humans while B. canis is considered rarely pathogenic. No identified bacterial factors or mechanisms account for this difference in virulence. To identify functional differences of these two bacteri...
ORGANISM(S): Brucella canis 
2012-12-01 | E-GEOD-34501 | biostudies-arrayexpress
GenomicsMicrosporum canis isolate:CBS 113480
Microsporum canis isolate:CBS 113480 Raw sequence reads
PRJNA563545 | ENA
ProteomicsCharacterization and proteomic analysis of extracellular vesicles recovered from serum of healthy and dogs naturally infected by Babesia canis
Canine babesiosis, a tick-borne disease, is characterized by protozoan parasites invading red blood cells. It is rapidly expanding in many European countries. Examining extracellular vesicles (EVs) and their protein cargo has the potential to offer crucial insights into the response to Babesia canis...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2024-04-23 | PXD047647 | Pride
Canine babesiosis Proteomics Extracellular vesicles Babesia canis Dog 
GenomicsCanis
Canis Genome sequencing
PRJNA494719 | ENA
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