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ProteomicsThe effect of cannabinoid receptor agonists on triple-negative breast cancer cell line (MDA-MB-231)
The endocannabinoid system (ECS) provides regulatory functions in several cellular and physiological processes. It has also been found to play a role in control of cancer development. Our group found that breast cancer cells responded to cannabinoid receptor (CB) agonist treatments. This leads the a...
ORGANISM(S): Homo sapiens (Human) 
2024-07-27 | PXD040666 | Pride
Breast cancer Triple-negative Proteomics Cannabinoid receptor agonists Human Endocannabinoid 
TranscriptomicsTranscription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity
We evaluated cutaneous contact hypersensitivity (CHS) in Cnr1-/-/Cnr2-/- animals using the obligate contact allergen 2,4-dinitrofluorobenzene (DNFB), which generates a specific cutaneous T-cell mediated allergic response upon repeated allergen contact. Allergic contact dermatitis affects about 5% of...
ORGANISM(S): Mus musculus 
2009-04-23 | E-GEOD-7694 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression profiling revealed peripheral effects of CB1 inverse agonists in improving insulin sensitivity and metabolic parameters
Inhibition of cannabinoid receptor 1 (CB1) has shown efficacy in reducing body weight and improving metabolic parameters, with the effects correlating with target engagement in the brain. Recently, the peripheral effects of inhibiting the CB1 receptor has been appreciated through studies in diet-ind...
ORGANISM(S): Mus musculus 
2010-06-21 | E-GEOD-21069 | biostudies-arrayexpress
GenomicsCannabinoid Receptor 2 Agonists Attenuate HIV Replication and Inflammatory Activation in HIV-infected Myeloid Cells
Cannabinoid Receptor 2 Agonists Attenuate HIV Replication and Inflammatory Activation in HIV-infected Myeloid Cells
PRJNA1054626 | ENA
GenomicsMolecular mechanisms of cannabinoid type II receptor agonists in a mouse model of psychological stress-induced cardiac injury revealed by whole transcriptomic analysis
Molecular mechanisms of cannabinoid type II receptor agonists in a mouse model of psychological stress-induced cardiac injury revealed by whole transcriptomic analysis
PRJNA867671 | ENA
UnknownNew Pyridone-Based Derivatives as Cannabinoid Receptor Type 2 Agonists.
Not available
S-EPMC8537746 | biostudies-literature
UnknownAntinociceptive effects of mixtures of mu opioid receptor agonists and cannabinoid receptor agonists in rats: Impact of drug and fixed-dose ratio.
Not available
S-EPMC5766417 | biostudies-literature
TranscriptomicsMolecular mechanisms of cannabinoid type II receptor agonists in a mouse model of psychological stress-induced cardiac injury revealed by whole transcriptomic analysis
To investigate the mechanisms of chronic psychological stress-induced cardiac injury and the protective mechanisms of cannabinoid type II agonists in a model of psychological stress-induced cardiac injury We constructed a mouse chronic psychological stress model based on a chronic unpredictable stre...
ORGANISM(S): Mus musculus 
2022-12-30 | GSE210820 | GEO
UnknownInteractions between cannabinoid receptor agonists and mu opioid receptor agonists in rhesus monkeys discriminating fentanyl.
Not available
S-EPMC4939121 | biostudies-literature
UnknownSynthetic cannabinoid receptor agonists are monoamine oxidase-A selective inhibitors.
Not available
S-EPMC10952593 | biostudies-literature
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